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Search Results - nanoparticle
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High Sensitivity and Specificity Biosensor
This sensor architecture enables signal amplification for detection of biomarkers and analytes at extremely low concentration Background Molecular diagnostics increasingly rely on sensitive detection of biomarkers such as nucleic acids, proteins, and cytokines in complex biological samples. Traditional biosensor probes often suffer from signal...
Published: 5/9/2026
|
Updated: 5/9/2026
|
Inventor(s):
Li-Jing Cheng
,
Ye Liu
Keywords(s):
analyte
,
assay
,
biomarkers
,
biosensor
,
diagnostic
,
immunoassay
,
magnetic
nanoparticle
s
,
molecular diagnostics
,
molecular probe
,
multiplexed detection
,
nanoparticle
,
nanoparticle
s
,
plasmonics
,
raman system
,
sensor
,
signal amplification
Category(s):
Diagnostics
Targeted
Nanoparticle
-Mediated HIF Stabilization in Myeloid Cells for Enhanced Transplant Tolerance
SHORT DESCRIPTION A PEG-PPS
nanoparticle
technology for targeted delivery of roxadustat to myeloid cells to promote transplantation tolerance. INVENTORS Edward Thorp* Northwestern University Feinberg School of Medicine, Department of Pathology Evan Scott* McCormick School of Engineering, Department...
Published: 5/7/2026
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Updated: 5/7/2026
|
Inventor(s):
Keywords(s):
Drug delivery
,
Immunotherapy
,
Nanoparticle
,
Therapeutics
,
Tolerance induction
,
Transplantation
Category(s):
Life Sciences > Therapeutics
Northwestern Startup: NanoGraf
Founded: 2012Northwestern Inventor: Harold KungMcCormick School of Engineering and Applied ScienceDepartment of Chemical and Biological EngineeringJiaxing Huang McCormick School of Engineering and Applied ScienceDepartment of Materials ScienceFormerly SiNode Systems, NanoGraf pursues advances in Lithium-ion battery anodes to transform a wide range of...
Published: 5/5/2026
|
Updated: 5/5/2026
|
Inventor(s):
Keywords(s):
Batteries
,
Energy and Infrastructure
,
Fuel Cell
,
Graphene
,
Nanoparticle
,
Startup with Northwestern IP
,
Sustainability
,
Sustainable Materials
Category(s):
Physical Sciences > Energy & Sustainability
,
Physical Sciences > Materials and Industrial Processes
Biomolecular Condensates as Protein Degradation Tools for Intracellular Targets
SHORT DESCRIPTION A targeted-protein degradation platform for intracellular targets, addressing resistant oncogenic and neurodegenerative targets. INVENTORS Shana Kelley* Weinberg College of Arts & Sciences, Department of Chemistry Yi Li * Principal Investigator NU Tech ID: NU 2025-050 IP...
Published: 5/7/2026
|
Updated: 4/27/2026
|
Inventor(s):
Keywords(s):
AD - Alzheimer’s Disease
,
Biologic
,
Biomolecular condensates
,
Cancer/Oncology
,
Drug delivery
,
Nanoparticle
,
Neurodegenerative disease
,
Neurologic disease
,
Neurology
,
PD - Parkinson's Disease
,
Platform technology
,
Targeted protein degradation
,
Targeted therapy
,
Therapeutics
Category(s):
Life Sciences > Therapeutics
,
Life Sciences > Biomarkers & Biomedical Research Tools
Nano-therapeutics Targeting Cholesterol Efflux Transporter in Macrophages for Cancer Immunotherapy
NU 2025-160 INVENTORS Jason Miska* Feinberg School of Medicine, Department of Neurological Surgery Peng Zhang* Feinberg School of Medicine, Department of Neurological Surgery SHORT DESCRIPTION Novel
nanoparticle
technology that modulates macrophage cholesterol metabolism to boost anti-tumor immunity in GBM. BACKGROUND Glioblastoma...
Published: 4/16/2026
|
Updated: 4/14/2026
|
Inventor(s):
Keywords(s):
Adjunct therapy
,
Brain cancer
,
Cancer/Oncology
,
CNS - Central Nervous System
,
Drug delivery
,
Immunotherapy
,
Nanoparticle
,
Neurologic disease
,
Therapeutics
Category(s):
Life Sciences > Therapeutics
Bi-specific Lipid
Nanoparticle
s for Boosting Antitumor Immunity in Glioblastoma
SHORT DESCRIPTION A bispecific lipid
nanoparticle
that bridges tumor-associated myeloid cells (TAMCs) and glioma cells by dual checkpoint blockade and simultaneously reprograms TAMCs into antitumor effectors via targeted delivery of a STING agonist. INVENTORS Maciej Lesniak* Northwestern University Feinberg School of Medicine,...
Published: 4/30/2026
|
Updated: 4/14/2026
|
Inventor(s):
Keywords(s):
Brain cancer
,
Cancer/Oncology
,
Drug delivery
,
Immunotherapy
,
Nanoparticle
,
Nanotechnology
,
Targeted therapy
,
Therapeutics
Category(s):
Life Sciences > Therapeutics
Advanced Pulsed-Laser Synthesis for Metal Carbides
NU 2025-190 SHORT DESCRIPTION A pulsed-laser synthesis method for making advanced metastable materials, including metal carbides and nitrides. INVENTORS Bryan Hunter* Alexis Magana Christopher Nowak * Principal Investigator NU 2025-190 IP STATUS Provisional Application Filed (joint with Harvard University) DEVELOPMENT...
Published: 4/22/2026
|
Updated: 4/10/2026
|
Inventor(s):
Keywords(s):
Materials
,
Metals
,
Nanoparticle
Category(s):
Physical Sciences > Materials and Industrial Processes
Targeted pH Sensitive Liposomes
NU 2020-170 INVENTORS Leo Gordon* Dong-Hyun Kim* Shuo Yang Wooram Park Taehoon Sim SHORT DESCRIPTION Liposomal
nanoparticle
s composed of pH-sensitive lipids and apolipoprotein that encapsulate andrographolide for lymphoma treatment. BACKGROUND Lymphoma, particularly diffuse large B-cell lymphoma (DLBCL), is the most common aggressive type...
Published: 3/11/2026
|
Updated: 3/11/2026
|
Inventor(s):
Keywords(s):
Blood & Lymphatic disease
,
Cancer/Oncology
,
Nanoparticle
,
Therapeutics
Category(s):
Life Sciences > Therapeutics
Facile Viral Clearance Validation Through the Development of Fluorescent Viral Surrogates
RPI ID: 2022-017-201 Innovation Summary: This system uses engineered fluorescent viral surrogates to validate viral clearance in bioprocessing. These surrogates mimic the properties of live viruses while being safe and traceable. Fluorescence tagging enables real-time monitoring during purification processes. The method reduces reliance on live virus...
Published: 3/10/2026
|
Updated: 3/10/2026
|
Inventor(s):
Runye Zha
,
Hannah Doss
,
Todd Przybycien
Keywords(s):
fluorescence
,
Nanoparticle
,
Viral clearance validation
,
viral surrogate particle
Category(s):
Biotechnology and the Life Sciences
Application-specific High Voltage Source
RPI ID: 2020-021-401 Innovation Summary: A high-voltage power supply system is developed for precision control and safety in demanding electrical environments. The system includes modular components for voltage scaling, fault detection, and thermal management. It supports applications in scientific instrumentation, industrial equipment, and medical...
Published: 3/10/2026
|
Updated: 3/10/2026
|
Inventor(s):
Edwin Fohtung
Keywords(s):
High voltage source
,
Materials analysis
,
Multiferroic
,
Nanoparticle
,
Nanopowders and thin films
,
sample environment
,
synchrotron
,
Thin Film
,
ultrafast laser
,
Voltage source
Category(s):
Computational Science and Engineering
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