Search Results - atherosclerosis

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Biomimetic HDL Nanoparticles for Treatment of Cancer, Immune and Inflammatory Disorders, and Cardiovascular Disease
SHORT DESCRIPTION Self-assembling biomimetic high-density lipoprotein nanoparticle (HDL NP) platform technology with a soft organic core, designed to more closely replicate key functional properties of mature human HDL for therapeutic use in cardiovascular disease, cancer, and inflammatory/immune disorders. INVENTORS Colby Thaxton* Northwestern...
Published: 6/16/2026   |   Updated: 6/16/2026   |   Inventor(s):  
Keywords(s): Atherosclerosis, Autoimmune disease, BIO2026, Breast cancer, Cancer/Oncology, Cardiology and Cardiovascular disease, Gene therapy, Immunology, Immunotherapy, Inflammation, Nanomaterials, Nanoparticle, Nanotechnology, Nucleic Acids, Platform technology, Prostate cancer, Research tool, Small molecule, Targeted therapy, Therapeutics
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools, Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Therapeutics
Targeted Nanofiber Therapy for Atherosclerosis – Enhanced Plaque Regression via Precise Drug Delivery
SHORT DESCRIPTION Nanofiber-based drug delivery system that targets atherosclerotic plaque and delivers a therapeutic agent locally to induce plaque regression for management of cardiovascular disease. INVENTORS Samuel Stupp* Weinberg College of Arts and Sciences, Department of Chemistry * Principal Investigator NU...
Published: 6/16/2026   |   Updated: 4/30/2026   |   Inventor(s):  
Keywords(s): Atherosclerosis, BIO2026, Biomaterials, Cardiology and Cardiovascular disease, Drug delivery, Nanomaterials, Nanotechnology, Self-assembly, Smart/Functional materials, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics
Methods for Diagnosis of Atherosclerosis
The identification of more sensitive and specific markers of atherosclerosis that are non-invasive and cost-effective may have profound impacts on public health. One such strategy involves the detection of marker genes or their products in blood or serum. Such markers may help identify high-risk patients with subclinical atherosclerosis who may benefit...
Published: 10/28/2024   |   Updated: 12/6/2022   |   Inventor(s): Paul Hwang
Keywords(s): ATHEROSCLEROSIS, FOS, IA1XXX, IAXXXX, IXXXXX, MARKER, Novel, Patent Category - Biotechnology
Category(s): Collaboration Sought > Licensing, TherapeuticArea > Cardiology, Application > Therapeutics, Application > Research Materials, Application > Diagnostics
A Self-Powered Bioelectronic Stent Sensor for Postoperative Blood Flow Rate Monitoring (UCLA Case No. 2022-276)
­Summary: UCLA researchers in the Department of Bioengineering have developed a miniaturized bioelectronic stent sensor that provides continuous, real-time, and reliable hemodynamic monitoring. Background: Diseases caused by arterial atherosclerosis are the leading cause of death and disability in the United States, affecting over 4.6 million...
Published: 7/17/2025   |   Updated: 11/21/2022   |   Inventor(s): Jun Chen, Geoffrey Colby, Guorui Chen
Keywords(s): Atherosclerosis, Biomaterial 3D Printing, Biomedical Engineering, Cardiovascular, Cardiovascular Disease, Heart Rate , Medical Device, Medical Devices and Materials, Medical Physics , Nanotechnology, Sensors, Smart medical device, Stent, wearable medical device
Category(s): Mechanical, Materials, Materials > Functional Materials, Materials > Nanotechnology, Medical Devices, Electrical > Mems
A New Method to Encapsulate Gas in Liposomes for Delivery to Diseased Tissue
NU 2006-048INVENTORSRobert MacDonald*David McPhersonShao-Ling HuangPatrick Kees SHORT DESCRIPTIONA method of producing nitrous oxide-containing liposomes for the treatement of diseaseBACKGROUNDNitrous oxide (NO) gas is a major signalling molecule in many tissues of the body. In the blood vessels, NO regulates bloodflow by increasing vessel diameter....
Published: 11/6/2025   |   Updated: 4/24/2020   |   Inventor(s):  
Keywords(s): Atherosclerosis, Drug delivery
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Novel Method of Enzymatic Plaque Digestion
NU 2008-157 Inventors Guillermo Ameer* Melina Kibbe* Jason Rubenstein Abstract Northwestern investigators have developed a novel plaque digestion composition to remove atherosclerotic plaque with minimal trauma to the arterial wall and minimal risk to the patient. No such approach has ever been utilized in patients. Balloons and mechanical blades...
Published: 11/6/2025   |   Updated: 10/27/2018   |   Inventor(s):  
Keywords(s): Atherosclerosis, Cardiology and Cardiovascular disease, Therapeutics
Category(s): Life Sciences > Therapeutics
Humanized Endothelial Specific TRPC3 Transgenic Mouse
Project: D2012-18 Strains: EST3Tg/C57BL6 and EST3Tg/Apoe-/- Type: Humanized transgenic mouse Background: In the U.S., atherosclerosis, hypertension and stroke are the major causes of death due to cardiovascular disease and remain most frequent vascular complications of metabolic diseases such as diabetes, obesity and metabolic syndrome. A common...
Published: 5/9/2024   |   Updated: 4/7/2014   |   Inventor(s): Guillermo Vazquez
Keywords(s): Atherosclerosis, Cardiovascular, Endothelial Dysfunction, Hypertension, Mouse, TRPC3, Vascular Permeability
Category(s): Tools