Search Results - biologic

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Northwestern Inventor: Joshua Leonard McCormick School of Engineering Chemical and Biological Engineering Syenex builds bioengineering technologies to unlock the future of human health. Leveraging the power of synthetic biology, we design scalable, precision-engineered components, empowering cell and gene therapy developers to cure disease and build...

Published: 5/5/2026 | Updated: 5/5/2026 | Inventor(s):

Keywords(s): Biologic, Biomedical, Drug delivery, Gene therapy, Platform technology, Research tool, Startup with Northwestern IP, Synthetic biology, Therapeutics, Vector/Plasmid

Category(s): Life Sciences > Biomarkers & Biomedical Research Tools, Life Sciences > Therapeutics

GDNF-Mimetic Self-Assembling Supramolecular Nanostructure to Enhance Survival and Function of Dopaminergic Neurons for Treatment of Parkinson's Disease

NU 2024-175 SHORT DESCRIPTION A self-assembling bioactive matrix that presents GDNF-mimetic peptides to support the viability, maturation, and function of dopaminergic neurons in cell replacement therapy for treatment of Parkinson’s Disease. INVENTORS Samuel Stupp* Weinberg College of Arts and Sciences, Department...

Published: 5/11/2026 | Updated: 4/30/2026 | Inventor(s):

Keywords(s): Biologic, Biomaterials, Cell delivery, CNS - Central Nervous System, CVA - Cerebrovascular Accident, Nanomaterials, Neurodegenerative disease, Neurologic disease, Neurology, PD - Parkinson's Disease, Scaffold, SCI - Spinal cord injury, TBI - Traumatic brain injury, Therapeutics

Category(s): Life Sciences > Therapeutics, Life Sciences > Biomarkers & Biomedical Research Tools, Life Sciences > Healthcare Devices, Tools & IT > Neurology

Bioactive, Conductive, and Antioxidant Supramolecular Polymer Hydrogels for Neural Applications

SHORT DESCRIPTION Biomaterial scaffold for neural cell culture and therapeutic implants that harnesses bioactive, conductive, and antioxidant properties to boost neural cell viability and maturation. INVENTORS Samuel Stupp* Weinberg College of Arts and Sciences, Department of Chemistry Anna Metlushko Bo...

Published: 5/11/2026 | Updated: 4/30/2026 | Inventor(s):

Keywords(s): Biologic, Biomaterials, CNS - Central Nervous System, Implantable devices, Neurology, Regenerative medicine, Scaffold, SCI - Spinal cord injury, Smart/Functional materials

Category(s): Life Sciences > Biomarkers & Biomedical Research Tools, Life Sciences > Healthcare Devices, Tools & IT > Neurology, Life Sciences > Therapeutics

Biomolecular Condensates as Protein Degradation Tools for Intracellular Targets

SHORT DESCRIPTION A targeted-protein degradation platform for intracellular targets, addressing resistant oncogenic and neurodegenerative targets. INVENTORS Shana Kelley* Weinberg College of Arts & Sciences, Department of Chemistry Yi Li * Principal Investigator NU Tech ID: NU 2025-050 IP...

Published: 5/7/2026 | Updated: 4/27/2026 | Inventor(s):

Keywords(s): AD - Alzheimer’s Disease, Biologic, Biomolecular condensates, Cancer/Oncology, Drug delivery, Nanoparticle, Neurodegenerative disease, Neurologic disease, Neurology, PD - Parkinson's Disease, Platform technology, Targeted protein degradation, Targeted therapy, Therapeutics

Category(s): Life Sciences > Therapeutics, Life Sciences > Biomarkers & Biomedical Research Tools

Anti-TYRP1 Bi-specific T cell Engager for Treatment of TYRP1-expressing melanoma

NU 2022-123 INVENTORS Irina Balyasnikova (Feinberg School of Medicine, Department of Neurological Surgery)* Isabelle Le Poole (Feinberg School of Medicine, Department of Dermatology)* SHORT DESCRIPTION A bispecific T cell engager that targets CD3+ T cells and TYRP1-expressing melanoma cells. BACKGROUND Melanoma is the deadliest form of skin...

Published: 4/14/2026 | Updated: 4/14/2026 | Inventor(s):

Keywords(s): Biologic, Cancer/Oncology, Immunotherapy, Melanoma, Targeted therapy, Therapeutics

Category(s): Life Sciences > Therapeutics

Responsive Probiotic Therapy for Local Detection and Treatment of IBD Flares

SHORT DESCRIPTION An engineered probiotic that senses intestinal inflammation via calprotectin and locally releases therapeutic antibodies in the gastrointestinal tract only during inflammatory flares. INVENTORS Arthur Prindle* McCormick School of Engineering, Department of Chemical and Biological Engineering Jonathan...

Published: 5/11/2026 | Updated: 4/14/2026 | Inventor(s):

Keywords(s): Autoimmune disease, Biologic, Cell therapy, Diagnostics, Gastrointestinal and Hepatic disease, IBD - Inflammatory bowel disease, Immunology, Immunotherapy, Inflammation, Synthetic biology, Therapeutics

Category(s): Life Sciences > Therapeutics

Recombinant Annexin Therapy for Muscle, Cardiac, and Neuronal Cell Membrane Repair

SHORT DESCRIPTION An annexin-based biological therapeutic that enhances the body's natural cell membrane repair process to reduce skeletal muscle, cardiac, and neuronal cell death and preserve tissue function. INVENTORS INVENTORS Elizabeth McNally* Feinberg School of Medicine, Department of Medicine (Cardiology Division) Alexis...

Published: 4/30/2026 | Updated: 4/14/2026 | Inventor(s):

Keywords(s): Biologic, Cardiomyopathy, DMD - Duchenne muscular dystrophy, Inflammation, Membrane injury and repair, Neurodegenerative disease, Rare diseases, SCI - Spinal cord injury, TBI - Traumatic brain injury, Therapeutics

Category(s): Life Sciences > Therapeutics

Antibodies for treatment of coronavirus disease

NU 2023-247 INVENTORS Huiping Liu* Deyu Fang* Hannah Mubarak Andrew Hoffmann Nurmaa Dashzeveg Lamiaa El-Shennawy Juncheng Wei Wuwei Tan Yang Shen SHORT DESCRIPTION Computationally redesigned antibodies targeting SARS-CoV-2 for treating COVID-19. BACKGROUND The continuous evolution of SARS-CoV-2 has allowed the virus to escape most therapeutic...

Published: 2/26/2026 | Updated: 2/26/2026 | Inventor(s):

Keywords(s): Antibody, Artificial Intelligence & Machine Learning, Biologic, Infectious disease, Research tool, Targeted therapy, Therapeutics

Category(s): Life Sciences > Therapeutics

The use of complex or fusion protein of soluble MIC (Smic) and antibody to treat MIC-negative cancer

NU 2019-146 INVENTORS Jennifer Wu* SHORT DESCRIPTION A fusion protein complex comprising soluble MIC and a non-blocking sMIC-neutralizing antibody that effectively activates CD8 T cells for the treatment of MIC-negative cancer. BACKGROUND Effective T cell co-stimulation is critical for durable tumor control, yet many current immunotherapies...

Published: 4/9/2026 | Updated: 12/3/2025 | Inventor(s):

Keywords(s): Antibody, Biologic, Cancer/Oncology, Immunotherapy, Infectious disease, Research tool, Targeted therapy, Therapeutics

Category(s): Life Sciences > Therapeutics

Spherical Nucleic Acids with Sheddable PEG Layers for Enhanced Tumor Targeting

NU 2017-169 INVENTORS Chad Mirkin* (Northwestern University, Weinberg College of Arts and Sciences, Department of Chemistry, Director of the International Institute for Nanotechnology (IIN)) Brian Meckes Wuliang Zhang SHORT DESCRIPTION For oncology applications, this invention offers spherical nucleic acids with an enzyme-cleavable PEG layer...

Published: 12/9/2025 | Updated: 10/30/2025 | Inventor(s):

Keywords(s): Biologic, Biomarker, Biomedical, Cancer/Oncology, Chemicals, Diagnostics, Drug delivery, Nanoparticle, Nanotechnology, Personalized medicine, Therapeutics

Category(s): Life Sciences > Therapeutics, Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Biomarkers & Biomedical Research Tools

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