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Search Results - cardiomyopathy
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Epigenetic Gene Editing in
Cardiomyopathy
to Improve Heart Function
SHORT DESCRIPTION A precision cardiac gene‑regulation platform that deletes a MYH7 enhancer to shift ventricular myosin isoform balance toward faster α‑MHC and activates upstream MYH6 enhancers to increase MYH6 expression and improve contractility, creating a dual toolkit for disease‑modifying therapy in
cardiomyopathy
and heart failure. INVENTORS Elizabeth...
Published: 5/13/2026
|
Updated: 5/12/2026
|
Inventor(s):
Keywords(s):
Cardiology and Cardiovascular disease
,
Cardiomyopathy
,
Gene therapy
,
Regenerative medicine
,
Therapeutics
Category(s):
Life Sciences > Therapeutics
Recombinant Annexin Therapy for Muscle, Cardiac, and Neuronal Cell Membrane Repair
SHORT DESCRIPTION An annexin-based biological therapeutic that enhances the body's natural cell membrane repair process to reduce skeletal muscle, cardiac, and neuronal cell death and preserve tissue function. INVENTORS INVENTORS Elizabeth McNally* Feinberg School of Medicine, Department of Medicine (Cardiology Division) Alexis...
Published: 4/30/2026
|
Updated: 4/14/2026
|
Inventor(s):
Keywords(s):
Biologic
,
Cardiomyopathy
,
DMD - Duchenne muscular dystrophy
,
Inflammation
,
Membrane injury and repair
,
Neurodegenerative disease
,
Rare diseases
,
SCI - Spinal cord injury
,
TBI - Traumatic brain injury
,
Therapeutics
Category(s):
Life Sciences > Therapeutics