Search Results - sci+-+spinal+cord+injury

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GDNF-Mimetic Self-Assembling Supramolecular Nanostructure to Enhance Survival and Function of Dopaminergic Neurons for Treatment of Parkinson's Disease
NU 2024-175 SHORT DESCRIPTION A self-assembling bioactive matrix that presents GDNF-mimetic peptides to support the viability, maturation, and function of dopaminergic neurons in cell replacement therapy for treatment of Parkinson’s Disease. INVENTORS Samuel Stupp* Weinberg College of Arts and Sciences, Department...
Published: 5/11/2026   |   Updated: 4/30/2026   |   Inventor(s):  
Keywords(s): Biologic, Biomaterials, Cell delivery, CNS - Central Nervous System, CVA - Cerebrovascular Accident, Nanomaterials, Neurodegenerative disease, Neurologic disease, Neurology, PD - Parkinson's Disease, Scaffold, SCI - Spinal cord injury, TBI - Traumatic brain injury, Therapeutics
Category(s): Life Sciences > Therapeutics, Life Sciences > Biomarkers & Biomedical Research Tools, Life Sciences > Healthcare Devices, Tools & IT > Neurology
Bioactive, Conductive, and Antioxidant Supramolecular Polymer Hydrogels for Neural Applications
SHORT DESCRIPTION Biomaterial scaffold for neural cell culture and therapeutic implants that harnesses bioactive, conductive, and antioxidant properties to boost neural cell viability and maturation. INVENTORS Samuel Stupp* Weinberg College of Arts and Sciences, Department of Chemistry Anna Metlushko Bo...
Published: 5/11/2026   |   Updated: 4/30/2026   |   Inventor(s):  
Keywords(s): Biologic, Biomaterials, CNS - Central Nervous System, Implantable devices, Neurology, Regenerative medicine, Scaffold, SCI - Spinal cord injury, Smart/Functional materials
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools, Life Sciences > Healthcare Devices, Tools & IT > Neurology, Life Sciences > Therapeutics
Recombinant Annexin Therapy for Muscle, Cardiac, and Neuronal Cell Membrane Repair
SHORT DESCRIPTION An annexin-based biological therapeutic that enhances the body's natural cell membrane repair process to reduce skeletal muscle, cardiac, and neuronal cell death and preserve tissue function. INVENTORS INVENTORS Elizabeth McNally* Feinberg School of Medicine, Department of Medicine (Cardiology Division) Alexis...
Published: 4/30/2026   |   Updated: 4/14/2026   |   Inventor(s):  
Keywords(s): Biologic, Cardiomyopathy, DMD - Duchenne muscular dystrophy, Inflammation, Membrane injury and repair, Neurodegenerative disease, Rare diseases, SCI - Spinal cord injury, TBI - Traumatic brain injury, Therapeutics
Category(s): Life Sciences > Therapeutics
Netrin-1 Mimetic Peptide Amphiphile Assemblies for Enhanced CNS Regeneration
NU 2024-174 INVENTORS Samuel Stupp* Cara Smith Zaida Alvarez Pinto SHORT DESCRIPTION Nanofiber-shaped supramolecular assemblies that mimic netrin-1 bioactivity to stimulate neurite growth and synaptic maturation for enhanced CNS regeneration. BACKGROUND Neurotrophic factors are essential for the development and regeneration of neurons; however,...
Published: 5/11/2026   |   Updated: 2/20/2026   |   Inventor(s):  
Keywords(s): AD - Alzheimer’s Disease, CNS - Central Nervous System, CVA - Cerebrovascular Accident, Nanomaterials, Nanotechnology, Neurodegenerative disease, Regenerative medicine, SCI - Spinal cord injury, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics
Sliding Bioactive Peptides for Therapeutic Delivery in CNS Regeneration
NU 2023-142 INVENTORS Samuel I. Stupp* Federico Lancia Madison E. Strong Matias A. Alvarez-Saavedra SHORT DESCRIPTION This technology involves the design and engineering of peptide amphiphile nanofibers that deliver bioactive peptides both extra- and intra-cellularly. The bioactive peptides can slide along these structures...
Published: 5/11/2026   |   Updated: 5/2/2025   |   Inventor(s):  
Keywords(s): Biomaterials, CNS - Central Nervous System, Drug delivery, Neurologic disease, Neurology, Regenerative medicine, SCI - Spinal cord injury, Therapeutics
Category(s): Life Sciences > Therapeutics
Human Spinal Cord Injury Organoids for Therapeutic Discovery
NU 2023-116 INVENTORS Nozomu Takata Nicholas Sather Samuel Stupp* SHORT DESCRIPTION A human organoid model to simulate spinal cord injury in vitro and test potential therapeutics. BACKGROUND Injury in organs triggers cellular and molecular rearrangements that induce intrinsic repair and regeneration, but the human central nervous system has...
Published: 1/16/2026   |   Updated: 7/3/2024   |   Inventor(s):  
Keywords(s): In vitro models, Neurology, Research tool, SCI - Spinal cord injury
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools