Search Results - neurology

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An Implantable Device for Restoring Muscle Function in Nerve or Muscle Impairment

A neuroprosthetic implant that uses existing nerve or muscle signals to replace damaged muscle and restores movement Problem: While prosthetics often replace entire limbs, smaller nerve or muscle injuries are common, severely impact daily life, and have limited treatment options. Facial paralysis is one example, where nerve damage causes muscle weakness,...

Published: 6/26/2026 | Updated: 6/25/2026 | Inventor(s): Niv Milbar, Cynthia Sung, Flavia Vitale, Gabriel Unger, Raghav Garg

Keywords(s): Bioengineering, Neurodegenerative Diseases, Neurology, Surgery

Category(s): Technology Classifications > Medical Devices, Technology Classifications > Robotics

Inhibitors of TRIP8b for Novel Mood Disorder Therapeutics

SHORT DESCRIPTION Novel inhibitors that disrupt TRIP8b-HCN binding to offer an alternative antidepressant mechanism for treatment of mood disorders. INVENTORS Gary Schiltz* Weinberg College of Arts and Sciences, Department of Chemistry Dane Chetkovich Ye Han Iredia Iyamu Kyle Lyman *...

Published: 6/17/2026 | Updated: 6/17/2026 | Inventor(s):

Keywords(s): Antidepressant, BIO2026, Depression, Mood disorder, Neurologic disease, Neurology, Psychiatric disorder, Targeted therapy, Therapeutics

Category(s): Life Sciences > Therapeutics

Bioactive Supramolecular Peptide Amphiphile Platforms for CNS In Vitro Models, CNS Regeneration, and Neurotherapeutic Delivery

SHORT DESCRIPTION A suite of self‑assembling peptide amphiphile nanostructures and hydrogels that mimic key neurotrophic factors, modulate ionic and electrical microenvironments, and protect therapeutic peptides to enhance neural survival, maturation, and regeneration across CNS diseases and injuries INVENTORS Samuel I Stupp Weinberg...

Published: 6/16/2026 | Updated: 6/16/2026 | Inventor(s):

Keywords(s): AD - Alzheimer’s Disease, ALS - Amyotrophic Lateral Sclerosis, BIO2026, Biomaterials, CNS - Central Nervous System, Drug delivery, Drug discovery, Drug screening, Hydrogel, In vitro models, Neurology, PD - Parkinson's Disease, Regenerative medicine, Research tool, Scaffold, SCI - Spinal cord injury, Smart/Functional materials, Therapeutics

Category(s): Life Sciences > Healthcare Devices, Tools & IT > Neurology, Life Sciences > Therapeutics

A CSF-Derived Therapy for Psychiatric Disorders

SHORT DESCRIPTION A synthetic soluble ⍺2δ-1-Fc protein to restore brain function in schizophrenia and autism. INVENTORS Peter Penzes* Northwestern University Feinberg School of Medicine, Department of Physiology Marc Dos Santos * Principal Investigator NU Tech ID: NU 2023-196 IP STATUS US...

Published: 6/16/2026 | Updated: 6/10/2026 | Inventor(s):

Keywords(s): ASD - Autism Spectrum Disorder, BIO2026, Biologic, Neurologic disease, Neurology, PSD - Psychotic spectrum disorder, Psychiatric disorder, Schizophrenia, Therapeutics

Category(s): Life Sciences > Therapeutics

Novel Aminotransferase Inhibitor Platform for the Treatment of Cancer and Neurological Disorders

SHORT DESCRIPTION Novel Aminotransferase Mechanism-Based Inhibitor (MBI) Platform Targeting OAT and GABA-AT as Novel Treatments for Cancer and Neurological Disorders. INVENTORS Richard Silverman* Weinberg College of Arts and Sciences, Department of Chemistry * Principal Investigator DEVELOPMENT...

Published: 6/17/2026 | Updated: 6/1/2026 | Inventor(s):

Keywords(s): AD - Alzheimer’s Disease, BIO2026, Cancer/Oncology, CNS - Central Nervous System, Colon cancer, Epilepsy, Gastric cancer, Liver cancer, Lung cancer, Neurodegenerative disease, Neurologic disease, Neurology, Pancreatic cancer, PD - Parkinson's Disease, Psychiatric disorder, Small molecule, Targeted therapy, Therapeutics

Category(s): Life Sciences > Therapeutics

Ultrafast, Sensitive, And Long-Lasting Bioelectrochemical Transistors

Supramolecular crown ethers and fluorinated polymers enable the formation of high ionic conductivity, water-impermeable artificial ion channels for bioelectronic transistor applications. Problem: Organic electrochemical transistors (OECTs) are central to bioelectronics by enabling sensitive amplification of weak biological signals through ionic-electronic...

Published: 5/28/2026 | Updated: 5/28/2026 | Inventor(s): Yuanwen Jiang, Yuhui Wang

Keywords(s): Bioengineering, Electronic Materials, Nanotechnology, Neurodegenerative Diseases, Neurology, Platform Technology

Category(s): Technology Classifications > Diagnostics, Technology Classifications > Hardware & Components, Technology Classifications > Materials, Technology Classifications > Medical Devices

Northwestern Startup: Akava Therapeutics

Founded: 2019 Northwestern Inventor: Richard Silverman Weinberg College of Arts and Sciences Department of Chemistry and Department of Molecular Biosciences Feinberg School of Medicine Department of Pharmacology AKAVA Therapeutics is developing first-in-class small molecule therapeutics that inhibit enzymes, inhibit cancer, and inhibit protein...

Published: 5/13/2026 | Updated: 5/13/2026 | Inventor(s):

Keywords(s): ALS - Amyotrophic Lateral Sclerosis, Neurodegenerative disease, Neurology, Therapeutics

Category(s): Life Sciences > Therapeutics

Antisense Oligonucleotides to Prevent Genetic Mis-Splicing for ALS/FTD Therapeutics

SHORT DESCRIPTION Antisense oligonucleotides (ASOs) that correct TDP‑43–dependent mis‑splicing of KCNQ2 thereby reducing neuronal hyperexcitability in ALS/FTD and related TDP‑43 proteinopathies. INVENTORS Evangelos Kiskinis* Northwestern University Feinberg School of Medicine, Department of Neurology Jonathan...

Published: 6/16/2026 | Updated: 5/7/2026 | Inventor(s):

Keywords(s): ALS - Amyotrophic Lateral Sclerosis, BIO2026, FTD - Frontotemporal Dementia, Neurodegenerative disease, Neurologic disease, Neurology, Nucleic Acids, Rare diseases, Targeted therapy, Therapeutics

Category(s): Life Sciences > Therapeutics

GDNF-Mimetic Self-Assembling Supramolecular Nanostructure to Enhance Survival and Function of Dopaminergic Neurons for Treatment of Parkinson's Disease

NU 2024-175 SHORT DESCRIPTION A self-assembling bioactive matrix that presents GDNF-mimetic peptides to support the viability, maturation, and function of dopaminergic neurons in cell replacement therapy for treatment of Parkinson’s Disease. INVENTORS Samuel Stupp* Weinberg College of Arts and Sciences, Department...

Published: 6/16/2026 | Updated: 4/30/2026 | Inventor(s):

Keywords(s): BIO2026, Biologic, Biomaterials, Cell delivery, CNS - Central Nervous System, CVA - Cerebrovascular Accident, Nanomaterials, Neurodegenerative disease, Neurologic disease, Neurology, PD - Parkinson's Disease, Scaffold, SCI - Spinal cord injury, TBI - Traumatic brain injury, Therapeutics

Category(s): Life Sciences > Therapeutics, Life Sciences > Biomarkers & Biomedical Research Tools, Life Sciences > Healthcare Devices, Tools & IT > Neurology

Bioactive, Conductive, and Antioxidant Supramolecular Polymer Hydrogels for Neural Applications

SHORT DESCRIPTION Biomaterial scaffold for neural cell culture and therapeutic implants that harnesses bioactive, conductive, and antioxidant properties to boost neural cell viability and maturation. INVENTORS Samuel Stupp* Weinberg College of Arts and Sciences, Department of Chemistry Anna Metlushko Bo...

Published: 6/16/2026 | Updated: 4/30/2026 | Inventor(s):

Keywords(s): BIO2026, Biologic, Biomaterials, CNS - Central Nervous System, Implantable devices, Neurology, Regenerative medicine, Scaffold, SCI - Spinal cord injury, Smart/Functional materials

Category(s): Life Sciences > Biomarkers & Biomedical Research Tools, Life Sciences > Healthcare Devices, Tools & IT > Neurology, Life Sciences > Therapeutics

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