Search Results - tbi+-+traumatic+brain+injury

6 Results Sort By:
Recombinant Annexin Therapy for Muscle, Cardiac, and Neuronal Cell Membrane Repair
SHORT DESCRIPTION An annexin-based biological therapeutic that enhances the body's natural cell membrane repair process to reduce skeletal muscle, cardiac, and neuronal cell death and preserve tissue function. INVENTORS INVENTORS Elizabeth McNally* Feinberg School of Medicine, Department of Medicine (Cardiology Division) Alexis...
Published: 6/16/2026   |   Updated: 6/10/2026   |   Inventor(s):  
Keywords(s): BIO2026, Biologic, Cardiomyopathy, DMD - Duchenne muscular dystrophy, Inflammation, Membrane injury and repair, Neurodegenerative disease, Rare diseases, SCI - Spinal cord injury, TBI - Traumatic brain injury, Therapeutics
Category(s): Life Sciences > Therapeutics
GDNF-Mimetic Self-Assembling Supramolecular Nanostructure to Enhance Survival and Function of Dopaminergic Neurons for Treatment of Parkinson's Disease
NU 2024-175 SHORT DESCRIPTION A self-assembling bioactive matrix that presents GDNF-mimetic peptides to support the viability, maturation, and function of dopaminergic neurons in cell replacement therapy for treatment of Parkinson’s Disease. INVENTORS Samuel Stupp* Weinberg College of Arts and Sciences, Department...
Published: 6/16/2026   |   Updated: 4/30/2026   |   Inventor(s):  
Keywords(s): BIO2026, Biologic, Biomaterials, Cell delivery, CNS - Central Nervous System, CVA - Cerebrovascular Accident, Nanomaterials, Neurodegenerative disease, Neurologic disease, Neurology, PD - Parkinson's Disease, Scaffold, SCI - Spinal cord injury, TBI - Traumatic brain injury, Therapeutics
Category(s): Life Sciences > Therapeutics, Life Sciences > Biomarkers & Biomedical Research Tools, Life Sciences > Healthcare Devices, Tools & IT > Neurology
STING Agonist 8803 for Blood-Brain Barrier Opening in Glioblastoma Treatment
SHORT DESCRIPTION Chemical compound that opens the blood-brain barrier to enhance delivery of therapeutics for treating glioblastoma. INVENTORS Amy Heimberger* Northwestern University Feinberg School of Medicine, Department of Neurological Surgery * Principal Investigator NU Tech ID: NU 2025-212 IP...
Published: 6/16/2026   |   Updated: 4/27/2026   |   Inventor(s):  
Keywords(s): AD - Alzheimer’s Disease, Adjunct therapy, ALS - Amyotrophic Lateral Sclerosis, Animal Model, Autoimmune disease, BIO2026, Bladder cancer, Brain cancer, Breast cancer, Cancer Treatment, Cancer/Oncology, Cervical cancer, CNS - Central Nervous System, Colon cancer, Drug delivery, Endometrial cancer, Gastric cancer, GBM - Glioblastoma, Head and neck cancer, Immunology, Immunotherapy, Liver cancer, Lung cancer, MS - Multiple Sclerosis, Neurodegenerative disease, Neurologic disease, Ovarian cancer, Pancreatic cancer, PD - Parkinson's Disease, Prostate cancer, Repurposed Drugs, Research tool, Small molecule, Targeted therapy, TBI - Traumatic brain injury, Therapeutics
Category(s): Life Sciences > Therapeutics, Life Sciences > Biomarkers & Biomedical Research Tools
Selective PAD2 Inhibitors for Neuroprotection in Traumatic Brain Injury
SHORT DESCRIPTION Novel PAD2-selective inhibitor platform targeting neuroinflammation to support both acute neuroprotection and long-term functional recovery as a first-in-class treatment of traumatic brain injury. INVENTORS Hasan Alam* Northwestern University Feinberg School of Medicine, Department of Surgery (Trauma...
Published: 6/16/2026   |   Updated: 4/27/2026   |   Inventor(s):  
Keywords(s): BIO2026, CNS - Central Nervous System, CVA - Cerebrovascular Accident, Neurodegenerative disease, Neuroinflammation, Neurologic disease, Neurology, Small molecule, Targeted therapy, TBI - Traumatic brain injury, Therapeutics
Category(s): Life Sciences > Therapeutics
Methods for assembling peptides into peptide amphiphile nanofibers
TITLE: Peptide Nanofiber Assembly for Enhanced Therapeutic Delivery NU 2020-081 SHORT DESCRIPTION This technology uses self-assembling peptide amphiphile nanofibers to protect and deliver therapeutic peptides. It reduces degradation and improves delivery efficiency for advanced treatment applications. BACKGROUND Peptide therapeutics offer promise...
Published: 6/16/2026   |   Updated: 10/21/2025   |   Inventor(s):  
Keywords(s): BIO2026, Drug delivery, Infectious disease, Nanomaterials, Neurodegenerative disease, Neurologic disease, Neurology, Neurovascular, TBI - Traumatic brain injury, Therapeutics
Category(s): Life Sciences > Therapeutics
Immunomodulatory Nanoparticles for the Therapeutic Intervention of Traumatic Brain Injury
NU 2019-030 INVENTORS John Kessler Sripadh Sharma ABSTRACT There is no decisive treatment for traumatic brain injury (TBI). After the primary trauma, secondary injury, largely mediated by blood-borne immune cells called monocytes, takes place causing damage to surrounding healthy cells. Furthermore, cellular and whole brain swelling (edema) resulting...
Published: 6/16/2026   |   Updated: 5/27/2022   |   Inventor(s):  
Keywords(s): Autoimmune disease, BIO2026, CNS - Central Nervous System, Immunology, Inflammation, Neurologic disease, Neurology, Targeted therapy, TBI - Traumatic brain injury, Therapeutics
Category(s): Life Sciences > Therapeutics