Search Results - infectious+disease

74 Results Sort By:
clampFISH 2.0: Fast, Cost-Effective RNA Detection Using Potent Fluorescent Probes
Molecular diagnostic using clamping fluorescent probes to amplify RNA detection signal of single-cell assay Problem: The molecular diagnostics market is expected to reach $13 billion by 2024, including cancer detection, blood screening, histology assays, tests for transplant compatibility, and inherited and infectious diseases (The World Market for...
Published: 6/29/2026   |   Updated: 6/26/2026   |   Inventor(s): Arjun Raj, Ian Dardani, Benjamin Emert, Sara Rouhanifard
Keywords(s): Bioengineering, Infectious Disease, Nanotechnology, Oncology
Category(s): Technology Classifications > Research Tools & Reagents, Technology Classifications > Diagnostics
Improved CD-4 Mimetic Compounds HIV Treatment
Indoline core CD-4 mimetics are a HIV treatment that trick the virus into entering a vulnerable “open” conformation, allowing antibody-dependent cellular toxicity. Problem: HIV impacts 38 million individuals worldwide, many of whom are receiving treatment. A barrier to successful treatment is viral rebound after cessation of antiviral therapy....
Published: 6/25/2026   |   Updated: 6/25/2026   |   Inventor(s): Amos Smith, Christopher Fritschi, Joseph Sodroski
Keywords(s): HIV/AIDS, Infectious Disease, Small Molecule
Category(s): Technology Classifications > Therapeutics
Small-Molecule Therapeutic for Stabilizing HIV-1 Envelope Proteins to Increase Immune Response
Small-molecule inhibitor that prolongs exposure of HIV-1 to broadly neutralizing antibodies to suppress viral entry and infection Problem: The human immunodeficiency virus (HIV-1) infects human cells through binding of its envelope proteins to surface-expressed CD4 and CCR5 receptors. Broadly neutralizing antibodies can recognize the native, functional...
Published: 6/25/2026   |   Updated: 6/25/2026   |   Inventor(s): Amos Smith, Althea Lang, Joseph Sodroski
Keywords(s): Drug Target, HIV/AIDS, Immunology, Infectious Disease
Category(s): Technology Classifications > Therapeutics, Technology Classifications > Chemical Processes and Synthesis
Exhaled Breath Condensate Collection Device for Respiratory Pathogen Testing
NU 2020-112 INVENTORS Christina Zelano* Gregory Lane SHORT DESCRIPTION A portable, self-administered exhaled breath condensate (EBC) collection device that enables patients to collect breath samples at home for SARS-CoV-2 or other respiratory pathogen detection, supporting direct, quantitative assessment of a person's infectiousness. BACKGROUND Determining...
Published: 6/17/2026   |   Updated: 6/17/2026   |   Inventor(s):  
Keywords(s): Biomarker, COVID-19, Diagnostics, Infectious disease
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Peptide Linkers for Modulating Antigen Immune Response in Cancer Vaccines
SHORT DESCRIPTION A novel non-biologically derived peptide linker technology enabling precise intracellular release of vaccine antigens to enhance immune activation. NU TECH ID NU 2024-124 INVENTORS Chad Mirkin* Weinberg College of Arts and Sciences, Department of Chemistry Tanner Fink *...
Published: 6/16/2026   |   Updated: 6/16/2026   |   Inventor(s):  
Keywords(s): BIO2026, Cancer/Oncology, Immunology, Immunotherapy, Infectious disease, Therapeutics, Vaccine
Category(s): Life Sciences > Therapeutics
A Solvent For The Extraction And Preservation Of mRNA At Room Temperature
A buffer that allows the extraction and long-term room temperature preservation of mRNA. Problem: mRNA is unstable in aqueous environments, so different formulations have been explored as water-free solvents for RNA. However, these solvents often contain toxic heavy metals, resulting in biological incompatibility. Additionally, current mRNA vaccines...
Published: 6/10/2026   |   Updated: 6/10/2026   |   Inventor(s): Daeyeon Lee, Kathleen Stebe, Hoang Dinh
Keywords(s): COVID-19, Infectious Disease, Platform Technology, Soft Materials
Category(s): Technology Classifications > Materials, Technology Classifications > Research Tools & Reagents
Assembly of Vaccines Using Cell-Free Integration of Viral Membrane Proteins into Liposomes
SHORT DESCRIPTION A cell-free method that assembles vaccines by integrating viral membrane proteins into liposomes, enabling rapid prototype production without cold chain requirements. INVENTORS Neha Kamat* McCormick School of Engineering, Department of Biomedical Engineering Hector Aguilar-Carreno Susan...
Published: 6/16/2026   |   Updated: 6/10/2026   |   Inventor(s):  
Keywords(s): BIO2026, Immunology, Infectious disease, Nanomaterials, Nanoparticle, Nanotechnology, Synthetic biology, Vaccine
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
Piperacillin for Targeted Lyme Disease Treatment
SHORT DESCRIPTION For infectious disease clinicians, this piperacillin-based therapeutic approach targets Lyme disease by inhibiting bacterial cell wall synthesis to reduce disease progression. INVENTORS INVENTORS Brandon Jutras* Northwestern University Feinberg School of Medicine, Department of Microbiology-Immunology ...
Published: 6/3/2026   |   Updated: 5/18/2026   |   Inventor(s):  
Keywords(s): Infectious disease, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics
Drug Repurposing for Age-Impaired Vascular Repair in COVID-19, Sepsis, and ARDS
SHORT DESCRIPTION Methods and compositions for treating COVID-19, sepsis, acute respiratory distress syndrome (ARDS), and cardiovascular diseases in elderly patients by either inhibiting vascular endothelial injury/inflammation or promoting FOXM1-dependent endothelial regeneration and vascular repair. INVENTORS Youyang Zhao Northwestern...
Published: 6/16/2026   |   Updated: 4/22/2026   |   Inventor(s):  
Keywords(s): ARDS - Acute Respiratory Distress Syndrome, BIO2026, COVID-19, Immunology, Infectious disease, Inflammation, Pulmonary disease, Therapeutics, Vascular disease, Vascular repair
Category(s): Life Sciences > Therapeutics
Antibodies for treatment of coronavirus disease
NU 2023-247 INVENTORS Huiping Liu* Deyu Fang* Hannah Mubarak Andrew Hoffmann Nurmaa Dashzeveg Lamiaa El-Shennawy Juncheng Wei Wuwei Tan Yang Shen SHORT DESCRIPTION Computationally redesigned antibodies targeting SARS-CoV-2 for treating COVID-19. BACKGROUND The continuous evolution of SARS-CoV-2 has allowed the virus to escape most therapeutic...
Published: 2/26/2026   |   Updated: 2/26/2026   |   Inventor(s):  
Keywords(s): Antibody, Artificial Intelligence & Machine Learning, Biologic, Infectious disease, Research tool, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics
1 2 3 4 5 6 7 8