Search Results - daeyeon+lee

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Targeted Delivery of Noble Gases via Microbubbles for Organ-Specific Therapeutic and Imaging Applications
Phospholipid encapsulation enables enhanced ultrasound contrast and localized delivery of therapeutic gases following hypoxic-ischemic injury. Problem: Noble gases such as xenon (Xe), Argon (Ar) and helium (He) are known to provide cardioprotective and neuroprotective effects in hypoxic-ischemic injuries, traumatic brain injury and post-cardiac arrest....
Published: 6/16/2026   |   Updated: 6/16/2026   |   Inventor(s): Rajarshi Chattaraj, Daeyeon Lee, Chandra Sandy Sehgal, Daniel Hammer
Keywords(s): Cardiovascular, Imaging Agents, Soft Materials
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Imaging, Technology Classifications > Therapeutics
Large-Scale Continuous Manufacturing of Micro and Nano-Scale Surface Wrinkles
Surface wrinkles able to control material properties of polymer films are produced across (a) large-areas by a combination of oxygen plasma treatment and sequential rolling. (b)-(c) wrinkles span the nanometer to micrometer scale, as demonstrated with scanning electron micrograph Scalable manufacturing technique to produce micro or nano-scale surface...
Published: 6/16/2026   |   Updated: 6/16/2026   |   Inventor(s): Daeyeon Lee, Kathleen Stebe, Shu Yang, Xu Zhang
Keywords(s):  
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Materials
Image-Based Soft-Sensor Approach to Automate Microfluidic Control
Leveraging open-source AI platforms, this technology enables automated image-based detection, prediction, and control of microfluidic single bubble/droplet formation. Problem: Given the incorporation of microfluidic bubble/droplet generation in many applications of science and medicine, improving their high-quality throughout with minimal human intervention...
Published: 6/30/2026   |   Updated: 6/15/2026   |   Inventor(s): Daeyeon Lee, Owen Land, Warren Seider
Keywords(s): Artificial Intelligence (AI) & Machine Learning, Imaging Agents, Microfluidics, Soft Materials, Software
Category(s): Technology Classifications > Computer Information Systems, Technology Classifications > Diagnostics, Technology Classifications > Imaging, Technology Classifications > Research Tools & Reagents, Technology Classifications > Robotics, Technology Classifications > Medical Devices
Method to Make Crack-Free Carbon Structures While Avoiding Shrinkage and Deformation
A method to make micropatterned carbon structures with pre-designed size and shape, avoiding shrinkage and deformation. Problem: Pyrolysis is a chemical process that involves the thermal decomposition of materials at elevated temperatures in an inert atmosphere. Applying pyrolysis to polymer templates can be used to fabricate micropatterned carbon...
Published: 6/12/2026   |   Updated: 6/12/2026   |   Inventor(s): Tiancheng Wang, Kathleen Stebe, Daeyeon Lee, Raymond Gorte, Renjing Huang
Keywords(s): Electronic Materials, Nanotechnology
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Materials, Technology Classifications > Research Tools & Reagents
Fast, On-Demand Manufacturing of Room Temperature-Stable RNA
A method enabling facile synthesis and purification of RNA in a stable format that does not require cold chain distribution. Problem: The cold storage conditions required in the distribution of RNA-based therapies presents a major roadblock toward expanding the utility of these medicines. RNA is susceptible to degradation in aqueous environment and...
Published: 6/11/2026   |   Updated: 6/11/2026   |   Inventor(s): Daeyeon Lee, Kathleen Stebe, Masoud Soroush, Dimitrios Papavassiliou
Keywords(s): Bioengineering, COVID-19, Platform Technology
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Therapeutics, Technology Classifications > Vaccines
A Solvent For The Extraction And Preservation Of mRNA At Room Temperature
A buffer that allows the extraction and long-term room temperature preservation of mRNA. Problem: mRNA is unstable in aqueous environments, so different formulations have been explored as water-free solvents for RNA. However, these solvents often contain toxic heavy metals, resulting in biological incompatibility. Additionally, current mRNA vaccines...
Published: 6/10/2026   |   Updated: 6/10/2026   |   Inventor(s): Daeyeon Lee, Kathleen Stebe, Hoang Dinh
Keywords(s): COVID-19, Infectious Disease, Platform Technology, Soft Materials
Category(s): Technology Classifications > Materials, Technology Classifications > Research Tools & Reagents
Continuous Bicontinuous Interfacially Jamming Emulsion Gels (Bijel) Fabrication For Complex, Three-Dimensional Structures
Adaptation of emulsion precursor materials to enable three-dimensional printing of bijels via direct ink writing (DIW) and co-solvent vaporization. Problem: Previously developed bijel fabrication methods produce structures with limited macroscale morphologies, such as fibers, particles, and other simple 2D structures. This restriction limits the applicability...
Published: 5/15/2026   |   Updated: 5/15/2026   |   Inventor(s): Daeyeon Lee, Kathleen Stebe, Jordan Raney, Philip Iaccarino, Damilola Lawal
Keywords(s): Bioengineering, Hydrogels, Platform Technology, Soft Materials
Category(s): Technology Classifications > Chemical Processes and Synthesis, Technology Classifications > Energy, Technology Classifications > Materials, Technology Classifications > Medical Devices
Heterostructured Film For Atmospheric Water Recovery
A nanoparticle-polymer film enables isothermal droplet formation and water recovery from humid air through capillary condensation on a porous surface. Problem: Conventional condensation of undersaturated water vapor can require energy-intensive cooling. Porous materials can condense water without cooling but often retain it inside voids. That makes...
Published: 5/6/2026   |   Updated: 4/30/2026   |   Inventor(s): Daeyeon Lee, Baek Min Kim, Amish Patel, Zachariah Vicars, Lilia Escobedo, R Bharath Venkatesh
Keywords(s): Nanotechnology, Soft Materials
Category(s): Technology Classifications > Agriculture & Environment, Technology Classifications > Materials
Adhesive Microparticle Formulation For Localized And Sustained Drug Delivery
A hairy, water-in-oil-in-water microemulsion for prolonged delivery of one or more active ingredients while adhering to target tissues. Problem: Microparticles are promising drug delivery platforms due to their biocompatibility and stability. However, existing particle-based drug delivery systems are unable to fulfill the needs for prolonged delivery...
Published: 10/3/2025   |   Updated: 11/13/2024   |   Inventor(s): Daeyeon Lee, Minjun Oh, Jaehyun Kim, Li-Wei Chang, Robert Mauck, George Dodge, Hyun (Michel) Koo
Keywords(s): Bioengineering, Dentistry, Drug Delivery, Drug Target
Category(s): Technology Classifications > Materials
Contactless, Reversible Material Deposition From Liquid Droplets To Solid Surfaces
A microfluidic device allowing spatiotemporal manipulation of droplets that can be applied to high-resolution analytical techniques. Problem: Electrowetting methods such as electrowetting-on-dielectric (EWOD) have been developed to support high-resolution analytical techniques such as mass spectrometry and atomic force microscopy. EWOD allows processing...
Published: 10/3/2025   |   Updated: 10/4/2024   |   Inventor(s): Daeyeon Lee, Junhyong Kim, Paradorn Rummaneethorn
Keywords(s): Microfluidics
Category(s): Technology Classifications > Research Tools & Reagents
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