Search Results - biomarkers

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Development of an Out-of-Hospital ECG-Based Diagnostic Biomarker to Distinguish Epileptic vs. Functional/Dissociative Seizures

This innovation presents a machine learning-based diagnostic tool that uses an electrocardiogram (ECG) signal to accurately distinguish between convulsive epileptic seizures and functional/dissociative seizures. Background: Diagnosing epileptic seizures (ES) versus functional/dissociative seizures (FDS) is complex and traditionally depends on long-term...

Published: 6/29/2026 | Updated: 6/24/2026 | Inventor(s): David Auerbach, Justin Ryan, Kyle Wagner

Keywords(s): biomarkers, epilepsy, seizures, Technologies

Category(s): Campus > Upstate Medical University, Technology Classifications > Diagnostics

Bi-Directional mTOR Blockade and Companion Biomarkers of Flare and Predictors of Therapeutic Efficacy in SLE

Novel therapeutic intervention targeting mTOR pathways combined with companion biomarkers enables personalized treatment of SLE and its liver complications. Background: Systemic lupus erythematosus (SLE) is a chronic, heterogeneous autoimmune disorder marked by dysregulated immune activity, systemic inflammation, and progressive damage across multiple...

Published: 6/29/2026 | Updated: 6/23/2026 | Inventor(s): Andras Perl

Keywords(s): biomarker diagnostics, biomarkers, drug efficacy, Technologies

Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering

Antibody-Based Blood Test for HEG1 Detection

Application HEG1 as a potential biomarker for early detection and risk assessment of hypertension and atherosclerosis. Key Benefits Addresses the importance of HEG1 in hypertension and atherosclerosis. Diagnostic for use in ELISA. A potential therapeutic target to treat hypertension and atherosclerosis. Market Summary Hypertension, defined...

Published: 6/22/2026 | Updated: 6/22/2026 | Inventor(s): Hanjoong Jo, Yerin Kim, Michael Clark, Shoutaro Tsuji

Keywords(s): Antibodies, Biomarkers, Cardiovascular Treatments, Hematology and Blood Products

Category(s): TechPub Algolia > Diagnostics

High Sensitivity and Specificity Biosensor

This sensor architecture enables signal amplification for detection of biomarkers and analytes at extremely low concentration Background Molecular diagnostics increasingly rely on sensitive detection of biomarkers such as nucleic acids, proteins, and cytokines in complex biological samples. Traditional biosensor probes often suffer from signal...

Published: 5/9/2026 | Updated: 5/9/2026 | Inventor(s): Li-Jing Cheng, Ye Liu

Keywords(s): analyte, assay, biomarkers, biosensor, diagnostic, immunoassay, magnetic nanoparticles, molecular diagnostics, molecular probe, multiplexed detection, nanoparticle, nanoparticles, plasmonics, raman system, sensor, signal amplification

Category(s): Diagnostics

Deep Learning-Enhanced Dual-Mode Multiplexed Optical Sensor for Point-Of-Care Diagnostics of Cardiovascular Diseases (Case No. 2026-178)

Summary: UCLA researchers in the Departments of Electrical and Computer Engineering and Bioengineering have developed a deep-learning-enhanced multiplexed optical biosensing platform that enables rapid, high sensitivity point-of-care quantification of multiple cardiac biomarkers for cardiovascular diagnostics. Background: Rapid and accessible cardiac...

Published: 3/24/2026 | Updated: 3/24/2026 | Inventor(s): Aydogan Ozcan, Dino Di Carlo, Gyeo-Re Han, Artem Goncharov, Merve Eryilmaz

Keywords(s): Biomarker, biomarkers, Cardiovascular, Cardiovascular Disease, cardiovascular diseases, cardiovascular monitoring, cardiovascular therapeutic solution, Deep Learning, Deep learning-based sensing, deep neural networks (DNN), neural network, neural networks, Optics, Point Of Care, point-of-care, point-of-care testing

Category(s): Electrical, Optics & Photonics, Diagnostic Markers, Medical Devices > Cardiac, Medical Devices

SMuRF: Software for Predicting Outcomes in Head and Neck Cancer

Application Novel data learning framework for integrating radiology and pathology data for discovering prognostic biomarkers and predicting outcomes in head and neck cancer. Key Benefits Integrates radiology and pathology data to improve risk prediction for head and neck cancer and support more informed treatment decisions. Can analyze multiple...

Published: 6/15/2026 | Updated: 3/10/2026 | Inventor(s): Bolin Song, Amaury Leroy, Anant Madabhushi

Keywords(s): Algorithm, AI, and Machine Learning, Biomarkers, Oncology Treatments

Category(s): TechPub Algolia > Software

Non-invasive Diagnostic for Meningiomas

Application A non-invasive molecular diagnostic tool that reliably predicts the tumor characteristics and risk of recurrence of meningiomas. Key Benefits Combines meningioma gene expression data, construction of a gene interaction network, and tumor histology data to diagnose and predict clinical outcomes. Complete analytical handling from specimen...

Published: 1/28/2026 | Updated: 1/28/2026 | Inventor(s): Ali Alawieh, Youssef Ismail, Tomas Garzon-Muvdi

Keywords(s): Algorithm, AI, and Machine Learning, Biomarkers, Oncology Treatments, Personalized Medicine, Platform, Screening Assays

Category(s): TechPub Algolia > Diagnostics

Anticancer Agent with N-Glycan Specificity

Application An engineered protein for targeting disease-associated N-glycans. Key Benefits High affinity, pH insensitive, no cofactors required. Applications in anticancer and antiviral therapeutics and research. Can aid in manufacturing monoclonal antibodies with desired N-glycosylation properties. Market Summary Glycosylation involves post-translation...

Published: 5/22/2026 | Updated: 11/3/2025 | Inventor(s): Eric J. Sundberg, Diego Sastre, Maros Huliciak

Keywords(s): Antibodies, Biologics, Biomarkers, Drug Discovery, Drug Target Identification, Enzyme and Protein Research, Microbiology and Infectious Disease Treatments, Oncology Treatments

Category(s): TechPub Algolia > Therapeutics

Multi-Particle System for Capture and Detection of Cellular and Molecular Analytes (Case No. 2025-267)

Summary: UCLA researchers in the Department of Bioengineering have developed a novel multi-particle system that selectively confines cells and molecular reactions within cavities formed by interacting particles. Background: Screening and selecting cells with specific, beneficial traits has become a vital process in using cell-derived products...

Published: 10/20/2025 | Updated: 7/29/2025 | Inventor(s): Dino Di Carlo, Alyssa Arnheim, Michael Mellody, Yuta Nakagawa, Lily Shang

Keywords(s): Assay, B Cell, barcode, Bioassay, biological assays, Biomarker, biomarkers, Biomaterial, capping particles, CAR-T cell platform, CAR-T cell therapy, cavities, cavity-containing particles, Cell and tissue culture, cell encapsulation, cell engineering, cell imaging, cell mapping, cell sorting, cell type identification, cell-based therapy, centrifugation, confinement, Diagnostic Platform Technologies (E.G. Microfluidics), Digital Microfluidics, Drug, Drug Delivery, Drug Discovery, drug screening, high throughput, high throughput assays, high throughput testing, high-throughput analysis, High-Throughput Screening, Immunoassay, Immunoassay Sense (Molecular Biology), Microfluidics, Microfluidics And Mem's, Microfluidics Nanosphere, microparticles, moieties, Nanoparticle, single cell analysis, single cell analysis and testing, Single cell data, single-cell resolution, single-cell trapping

Category(s): Life Science Research Tools, Life Science Research Tools > Cell Counting And Imaging, Life Science Research Tools > Lab Equipment, Life Science Research Tools > Microscopy And Imaging, Life Science Research Tools > Microfluidics And Mems, Medical Devices, Platforms

Algorithm for Identifying Images of Fluorescently-Labeled Cells

Improves the ability to distinguish multiple fluorophores with overlapping emission spectra in biological images of labeled cells by a factor of two or more. Background: Cells (including normal and tumor cells), tissues, microbial communities, and other biological systems generally consist of multiple interacting components, especially proteins...

Published: 6/11/2026 | Updated: 5/13/2025 | Inventor(s): Alex Valm, Yunlong Feng

Keywords(s): bacterial cells, bacterial infection, bioengineering, biofilm control, bioinformatics, biomarker diagnostics, biomarkers, cancer, cell biology, computational biology, dental, diagnostics, digital image processing, fluorescence, fluorescence spectroscopy, gene expression analysis, image analysis, image processing, machine learning, medical imaging, microbial pathogenesis, personalized medicine, RNA, saliva, scanning microscopy, Technologies

Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Medical Imaging, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines

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