Search Results - obesity+metabolic+disease+and+diabetes

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An All-In-One “Swiss Army Knife” Tool To Edit Genes And Regulate Their Expression Without Off-Target Effects And Toxicity
A flexible toolkit for human gene editing, activation, and repression that can be applied in orthogonally and in various disease models. Problem: There is increasing demand for technologies that can simultaneously edit the genome and regulate the transcriptome without relying on toxic double-stranded breaks. Currently, treating complex diseases such...
Published: 5/5/2026   |   Updated: 5/5/2026   |   Inventor(s): Xue Sherry Gao, Tyler Daniel, Hongzhi Zeng, Qichen Yuan
Keywords(s): Bioengineering, Cell Therapy, Gene Editing, Genetic Disorders, Neurodegenerative Diseases, Obesity Metabolic Disease and Diabetes, Oncology, Orphan Disease, Pulmonary
Category(s): Technology Classifications > Research Tools & Reagents, Technology Classifications > Therapeutics
Interoceptomimetics: Dietary Supplements to Enhance Exercise Motivation and Performance
Enhancing exercise performance by modulating the activity of motivation-generating brain regions via stimulation of cannabinoid (CB1) receptors of the enteric nervous system. Problem: An increase in sedentary lifestyles driven by the modernization of society has led to a surge in several metabolic and neurological diseases worldwide. Although exercise...
Published: 4/30/2026   |   Updated: 4/30/2026   |   Inventor(s): Christoph Thaiss, John Nicholas Betley
Keywords(s): Aging, Cardiovascular, Healthcare IT, Microbiome, Neurology, Obesity Metabolic Disease and Diabetes, Regenerative Medicine, Small Molecule
Category(s): Technology Classifications > Food Science and Nutrition, Technology Classifications > Therapeutics
LNP Delivery of Gene-Editing Machinery to Cure Hereditary Tyrosinemia Type 1g
Problem: Hereditary tyrosinemia type 1 (HT1) is a genetic metabolic disease caused by the inability to break down tyrosine, an amino acid present in many meats, dairy products, fruits, and nuts. This disease can be fatal within the first few months of life and increases the risk of liver cancer. The current treatment involves a strict drug regimen and...
Published: 8/21/2025   |   Updated: 7/10/2024   |   Inventor(s): Kiran Musunuru, Madelynn Whittaker, Xiao Wang, William Peranteau, Cara Berkowitz, Ana Dumitru
Keywords(s): Gene Editing, Genetic Disorders, Obesity Metabolic Disease and Diabetes
Category(s): Technology Classifications > Therapeutics
Topical Treatment for Autoimmune Disorders
Treatment method for autoimmune diseases such as diabetes, multiple sclerosis, atherosclerosis, and rheumatoid arthritis using skin application of a vitamin D analog where topical treatment leads to systemic immunoregulation. Problem: Immunomodulatory drugs are typically administered systemically and often lead to severe side effects. Moreover,...
Published: 7/31/2025   |   Updated: 5/3/2024   |   Inventor(s): Taku Kambayashi
Keywords(s): Immunology, Obesity Metabolic Disease and Diabetes
Category(s): Technology Classifications > Therapeutics
Physiology-independent control algorithm for an artificial pancreas
An insulin pump control system that works automatically without user input Problem: Diabetic patients can use insulin pumps to deliver insulin after a meal. Continuous glucose monitoring (CGM) systems are also used to record glucose levels throughout the day. These systems could be unified via a closed-loop control algorithm to create an artificial...
Published: 1/17/2025   |   Updated: 1/31/2020   |   Inventor(s): Insup Lee
Keywords(s): Drug Delivery, Obesity Metabolic Disease and Diabetes
Category(s): Technology Classifications > Medical Devices
The g3mclass Software for Multiclass Disease Diagnosis and Reporting.
Diagnostic software to stratify patients on biomarkers and therapeutic targets. Problem: Targeted therapy has revolutionized the treatment of cancer. The efficacy of such therapy is highly dependent on target levels that may increase, decrease, or remain unchanged in the tumor compared to healthy tissue. In clinical practice, the target’s...
Published: 5/11/2026   |   Updated: 8/12/2019   |   Inventor(s): Marina Guvakova
Keywords(s): Artificial Intelligence (AI) & Machine Learning, Data Science, Drug Target, Immunoncology, Men's Health, Neurology, Obesity Metabolic Disease and Diabetes, Oncology, Software, Surgery, Women's Health
Category(s): Technology Classifications > Animal Health, Technology Classifications > Diagnostics, Technology Classifications > Therapeutics, Technology Classifications > Testing & Measurement