Search Results - brain+delivery

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Targeted Nanocarriers for Brain Inflammation and Cancer Cachexia
Nanocarriers deliver anti-inflammatory therapeutics across the blood-brain barrier to activated microglia Background Delivering therapeutics to the brain remains a major drug-development challenge because the blood-brain barrier restricts systemic agents from reaching therapeutically relevant concentrations in the central nervous system. This barrier...
Published: 5/7/2026   |   Updated: 5/7/2026   |   Inventor(s): Oleh Taratula, Olena Taratula, Yoon Tae Goo
Keywords(s): anti-inflammatory, Anti-inflammatory drugs, biodegradable, biodistribution, blood-brain barrier, brain delivery, brain inflammation, CNS drug delivery, cytokine expression, Drug Delivery, Drug Development, glutathione, immune cell, immunohistochemistry, irak4 inhibitor, lipopolysaccharides, microglia, mouse model, nanocarrier, nanocarriers, nanomedicine, neuroinflammation, pancreatic cancer, pharmaceuticals, pharmacokinetics, preservation, pro-inflammatory cytokine, small molecules, water-soluble, weight maintenance
Category(s): Therapeutics
Receptor-Ligand Combination for Specific Drug Delivery to the Brain
Molecule Crosses the Blood-Cerebrospinal Fluid Barrier to Deliver Therapy into Targeted CellsThis engineered receptor-ligand combination targets and crosses the brain barriers of mammals to deliver drugs and therapeutics to the brain. About 12 percent of all deaths worldwide are caused by neurological disorders such as Alzheimer’s, Parkinson’s...
Published: 1/20/2026   |   Updated: 5/16/2019   |   Inventor(s): Hector Mendez-Gomez, Nicholas Muzyczka
Keywords(s): Blood-brain barrier, brain delivery, brain-specific drug delivery, Gene Therapy, receptor-mediated transcytosis
Category(s): Technology Classifications > Human Health Care > Drug Delivery, Technology Classifications > Human Health Care > Gene Therapy, Technology Classifications > Research Tools > Therapeutics