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Search Results - biodegradable
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Targeted Nanocarriers for Brain Inflammation and Cancer Cachexia
Nanocarriers deliver anti-inflammatory therapeutics across the blood-brain barrier to activated microglia Background Delivering therapeutics to the brain remains a major drug-development challenge because the blood-brain barrier restricts systemic agents from reaching therapeutically relevant concentrations in the central nervous system. This barrier...
Published: 5/7/2026
|
Updated: 5/7/2026
|
Inventor(s):
Oleh Taratula
,
Olena Taratula
,
Yoon Tae Goo
Keywords(s):
anti-inflammatory
,
Anti-inflammatory drugs
,
biodegradable
,
biodistribution
,
blood-brain barrier
,
brain delivery
,
brain inflammation
,
CNS drug delivery
,
cytokine expression
,
Drug Delivery
,
Drug Development
,
glutathione
,
immune cell
,
immunohistochemistry
,
irak4 inhibitor
,
lipopolysaccharides
,
microglia
,
mouse model
,
nanocarrier
,
nanocarriers
,
nanomedicine
,
neuroinflammation
,
pancreatic cancer
,
pharmaceuticals
,
pharmacokinetics
,
preservation
,
pro-inflammatory cytokine
,
small molecules
,
water-soluble
,
weight maintenance
Category(s):
Therapeutics
Delivery of sustained local and systemic immunomodulation
Reducing treatment burden with continuous immune activation Background: Current immunotherapy approaches face significant limitations in both delivery and patient experience. Standard treatments rely on either systemic intravenous injections of antibodies or small molecules that require frequent clinic visits, or localized injections that provide...
Published: 4/2/2026
|
Updated: 6/13/2025
|
Inventor(s):
Srinivas Sridhar
,
Needa Brown
,
Jennifer Guerriero
,
Alexander Gottlieb
Keywords(s):
biocompatible
,
Biodegradable
,
Biomaterials
,
Cancer
,
Drug Delivery
,
Immunoengineering
,
immunotherapy
,
implant
,
Nanomedicine
Category(s):
Technology Classifications > 1. Life Science > Therapeutics
Highly Elastic Biomaterial Development for the Lower Urinary Tract (UCLA Case No. 2024-060)
Summary: UCLA researchers in the Departments of Urology and Chemical & Biomolecular Engineering have developed biomimetic, elastic biomaterial for use in urinary tract reconstruction. Background: Lower urinary tract (LUT) reconstructions have a high failure rate leading to complications including urinary tract infections and leakage. There is...
Published: 2/14/2025
|
Updated: 10/20/2023
|
Inventor(s):
Renea Sturm
,
Nasim Annabi
Keywords(s):
biodegradable
,
Biomaterial
,
bladder
,
elastin
,
lower urinary tract (LUT)
,
surgical tool
,
suturable biomaterial
,
Tissue Engineering
,
tissue regeneration
,
urethra
,
urinary tract reconstruction
Category(s):
Medical Devices
,
Medical Devices > Surgical Tools
Biodegradable
Plastic Made from Plant Materials
Uses Byproduct of Paper Production for Cost-Competitive Production of Synthetic Fibers, Food and Beverage Containers, Films and ResinsThis cost-competitive bioplastic is more environmentally friendly than plastics made from petrochemicals. Most plastics are produced from crude oil or natural gas, disappearing resources that will continue to rise in...
Published: 1/20/2026
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Updated: 5/16/2019
|
Inventor(s):
Laurent Mialon
,
Stephen Miller
Keywords(s):
Biodegradable
,
Lignin
,
Polyethylene Terephthalate
,
polymer
,
Syringaldehyde
,
Vanillin
Category(s):
Technology Classifications > Engineering > Chemical
Device for Improved Efficiency of Tubes Used in Stents and Other Medical Devices
Cleans Interior and Exterior of Capillary Tubes to Improve Flow of Fluid This cleaning device for tubing used in stents, other medical devices, and flexible piping systems allows internal and external cleaning of capillary tubes to improve the flow of fluid. The worldwide market for stents, which are mesh tubes used to hold open arteries, is expected...
Published: 1/20/2026
|
Updated: 5/14/2019
|
Inventor(s):
Hitomi Greenslet
,
Xueyu Du
,
Valens Nteziyaremye
Keywords(s):
Biodegradable
,
Magnesium
,
micro machine parts
,
microprocess polishing
,
Polishing
,
Stent
,
stent manufacturing
Category(s):
Technology Classifications > Engineering
,
Technology Classifications > Engineering > Mechanical