Search Results - pharmacokinetics

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Targeted Nanocarriers for Brain Inflammation and Cancer Cachexia
Nanocarriers deliver anti-inflammatory therapeutics across the blood-brain barrier to activated microglia Background Delivering therapeutics to the brain remains a major drug-development challenge because the blood-brain barrier restricts systemic agents from reaching therapeutically relevant concentrations in the central nervous system. This barrier...
Published: 5/7/2026   |   Updated: 5/7/2026   |   Inventor(s): Oleh Taratula, Olena Taratula, Yoon Tae Goo
Keywords(s): anti-inflammatory, Anti-inflammatory drugs, biodegradable, biodistribution, blood-brain barrier, brain delivery, brain inflammation, CNS drug delivery, cytokine expression, Drug Delivery, Drug Development, glutathione, immune cell, immunohistochemistry, irak4 inhibitor, lipopolysaccharides, microglia, mouse model, nanocarrier, nanocarriers, nanomedicine, neuroinflammation, pancreatic cancer, pharmaceuticals, pharmacokinetics, preservation, pro-inflammatory cytokine, small molecules, water-soluble, weight maintenance
Category(s): Therapeutics
2022-222 A Wearable Aptamer Microneedle Patch for Continuous Minimally-Invasive Biomonitoring
Summary: UCLA researchers in the Department of Bioengineering have developed a novel wearable device for real-time, minimally-invasive medication monitoring. Background: Current medication dosing is determined by taking the average therapeutic dose of a small patient sample size. However, this is often inaccurate for many individuals and the recommended...
Published: 2/14/2025   |   Updated: 9/29/2022   |   Inventor(s): Sam Emaminejad, Shuyu Lin, Jialun Zhu, Xuanbing Cheng
Keywords(s): Biomonitoring, Drug, Drug Delivery, Drug Development, Drug Discovery, Drug Resistance, Invasiveness Of Surgical Procedures, Microneedle array, non-invasive drug monitoring, Personalized Pharmacotherapy, Pharmaceutical Drug, Pharmacokinetics, Pharmacology, Prescription Drug, Therapeutic Drug Monitoring, Therapeutics & Vaccines
Category(s): Life Science Research Tools, Medical Devices, Materials > Nanotechnology