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Search Results - zhiqiang+an
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clampFISH 2.0: Fast, Cost-Effective RNA Detection Using Potent Fluorescent Probes
Molecular diagnostic using clamping fluorescent probes to amplify RNA detection signal of single-cell assay Problem: The molecular diagnostics market is expected to reach $13 billion by 2024, including cancer detection, blood screening, histology assays, tests for transplant compatibility, and inherited and infectious diseases (The World Market for...
Published: 6/29/2026
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Updated: 6/26/2026
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Inventor(s):
Arjun Raj
,
Ian Dardani
,
Benjamin Emert
,
Sara Rouhanifard
Keywords(s):
Bioengineering
,
Infectious Disease
,
Nanotechnology
,
Oncology
Category(s):
Technology Classifications > Research Tools & Reagents
,
Technology Classifications > Diagnostics
Lipid nanoparticles for lung-targeted mRNA delivery
This technology is a new lipid nanoparticle system that can safely, specifically, and efficiently deliver mRNA to a patient’s lungs. Background: Therapeutics that deliver mRNA to a patient’s lungs offer significant potential for treating a broad spectrum of lung diseases. However, specifically and efficiently delivering mRNA to lung tissue...
Published: 6/22/2026
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Updated: 6/21/2026
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Inventor(s):
Yamin Li
,
David Popoola
,
Zhi Cao
,
Yuqin Men
Keywords(s):
biomaterials
,
chemistry
,
drug delivery
,
gene therapy
,
nanoparticle drug delivery
,
RNA
,
Technologies
Category(s):
Campus > Upstate Medical University
,
Technology Classifications > Therapeutics and Vaccines
Systems and Methods for Concurrent Biochemical Immunoassay and Cellular Traction Force Measurement in Hydrogels
This invention relates to a platform that couples bead-based immunoassays with 3D traction force microscopy (TFM) within a single hydrogel substrate to quantify time-resolved biochemical cues and cell-generated mechanical forces at matched locations. This invention allows researchers to directly test how local molecular cues influence cell mechanics...
Published: 6/17/2026
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Updated: 3/23/2026
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Inventor(s):
Alex McGhee
,
Kelvin Pond
,
A Departmental Work
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics > Sensors and Detection
,
Technology Classifications > Engineering & Physical Sciences > Photonics
,
Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation
,
Technology Classifications > Life Sciences > Diagnostics
,
Technology Classifications > Research Tools > Screening assays
Dark Eye Harvester
This invention involves using an insulated light-proof chamber that allows the harvesting of eyes or another light-sensitive biomaterial without light exposure, allowing visual rhodopsin to regenerate more efficiently. The chamber has a cylindrical shape and is attached to a chest cooler with handles on top to rotate the walls. The chamber has multiple...
Published: 6/17/2026
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Updated: 2/9/2026
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Inventor(s):
A Departmental Work
,
Michael Brown
Keywords(s):
Category(s):
Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation
,
Technology Classifications > Research Tools
Soy Protein Based, UV Curable Resin Compositions
Researchers at NDSU have developed a biodegradable and compostable bioplastic, which potentially eliminates the generation of long-lasting microplastics in products where this technology is used. This is a replacement for certain products that are made from high-density polyethylene and polypropylene. The new plastic is an improved Soy Protein Isolate...
Published: 4/14/2026
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Updated: 1/30/2026
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Inventor(s):
Long Jiang
,
Qian Ma
Keywords(s):
Biobased Technology
Category(s):
Technologies
,
Technologies > Chemistry & Materials
“Smart” Glucose-Responsive Insulin
Technology Summary A "smart" or glucose-responsive insulin that can automatically respond to changes in a patient’s blood stream and help treat patients with type 1 diabetes. This technology comprises compositions that integrate a zwitterionic polymer, insulin moieties, saccharide moieties, and saccharide binding molecules to create...
Published: 1/9/2026
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Updated: 1/9/2026
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Inventor(s):
Zhiqiang Cao
Keywords(s):
Category(s):
Technology Category > Biological materials
,
Technology Category > Chemical Processing/Synthesis
,
Technology Category > Drug Delivery
,
Technology Category > Process/Procedure
,
Technology Category > Small molecule
,
Technology Category > Therapeutics
,
Technology Category > Life Science
Therapeutic backbone and scaffold modification in the physiological environment
This technology enables precise, water-based chemical modification of proteins at their C-terminus using a single, easily removable reagent, preserving protein structure and function and allowing attachment of diverse functional groups for therapeutic, research, and diagnostic applications. Background: Proteins and polypeptides play a central role...
Published: 5/1/2026
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Updated: 12/19/2025
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Inventor(s):
Qiang Zhang
Keywords(s):
antibody therapy
,
GLP-1 secretion
,
Insulin
,
protein engineering
,
Technologies
Category(s):
Campus > University at Albany
,
Technology Classifications > Biomedical Science and Engineering
Protein Polymers for Organelle Engineering
Application Protein polymers enabling engineering of human membraneless organelles. Key Benefits Versatile applications across immunotherapy, cell therapy, and other therapeutic modalities. High biocompatibility with minimal reactivity with endogenous molecules. Deployable for organelle-level functionalization of human cells. Market Summary Proteins...
Published: 5/22/2026
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Updated: 11/7/2025
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Inventor(s):
Felipe Quiroz
,
Ian Sicher
,
Spencer Hayes
,
Maria Giraldo-Castaño
,
Mariell Pascual
,
Alexa Avecilla
Keywords(s):
Biomaterials
,
Cell Therapy
,
Immunotherapy
,
Protein and Peptide Therapeutics
,
Regenerative Medicine
,
Research Tools
Category(s):
TechPub Algolia > Therapeutics
Task-Oriented Edge Metaverse for Smart Cities and Critical Systems
This invention introduces a task-oriented “Microverse” architecture that creates temporary, edge-based digital twins for 5G/IoT network slices. By combining real-time data fusion, per-task blockchain security, and immersive VR/AR interfaces, it delivers sub-second situational awareness and secure collaboration for smart cities, infrastructure,...
Published: 11/12/2025
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Updated: 10/17/2025
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Inventor(s):
Yu Chen
,
Qian Qu
Keywords(s):
Technologies
Category(s):
Campus > Binghamton University
Droplet-Based Single-Cell Epigenomic Assay
THE CHALLENGE A major challenge in single-cell DNA methylation profiling lies in the inefficiency and high cost of current methods, which rely on labor-intensive, plate- or tube-based workflows that are difficult to scale. These traditional approaches not only require multiple manual steps and expensive reagents but also suffer from significant DNA...
Published: 10/20/2025
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Updated: 8/14/2025
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Inventor(s):
Chang Lu
,
Qiang Zhang
Keywords(s):
Category(s):
Technology Classifications > Biotechnology
,
Technology Classifications > Biomedical
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