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Search Results - nnos
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Neuronal nitric oxide synthase (
nNOS
) inhibitors for targeted therapy of melanoma and neurodegenerative disorders
NU 2016-137B INVENTORS Richard Silverman Weinberg College of Arts and Sciences, Department of Chemistry SHORT DESCRIPTION Novel highly selective neuronal nitric oxide synthase (
nNOS
) inhibitors for targeted therapy of melanoma and other cancers with high expression of nNOS (e.g., gliomas, ovarian cancer) as well as neurodegenerative...
Published: 6/17/2026
|
Updated: 6/16/2026
|
Inventor(s):
Keywords(s):
AD - Alzheimer’s Disease
,
ALS - Amyotrophic Lateral Sclerosis
,
AUTM26C1
,
BIAUTM1
,
BIO2026
,
Cancer/Oncology
,
HD - Huntington's Disease
,
Melanoma
,
Neurodegenerative disease
,
Neuroinflammation
,
Neurologic disease
,
nNOS
,
PD - Parkinson's Disease
,
Small molecule
,
Targeted therapy
,
Therapeutics
Category(s):
Life Sciences > Therapeutics
Use of Neuronal NOS Inhibitors for Alzheimer's Therapeutic Intervention
PROPOSED TITLE (cut & paste into Alternate Title): Use of Neuronal NOS Inhibitors for Alzheimer's Therapeutic Intervention NU 2023-007 SHORT DESCRIPTION A small molecule based approach that mitigates Alzheimer's neurodegeneration by inhibiting neuronal nitric oxide synthase to prevent tau phosphorylation and reduce Aβ oligomer formation. INVENTORS Richard...
Published: 6/16/2026
|
Updated: 4/27/2026
|
Inventor(s):
Keywords(s):
AD - Alzheimer’s Disease
,
BIO2026
,
Covalent inhibitor
,
Kinase Inhibitor
,
Neurodegenerative disease
,
Neurology
,
nNOS
,
Small molecule
,
Targeted therapy
,
Therapeutics
Category(s):
Life Sciences > Therapeutics