Search Results - yueming+zhu

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Molecular Ruler for Quantifying Steady-State and Population Distribution of Photo-Generated Charge Carriers
Provides Quantitative Information on the Steady-State Hot Carriers in Semiconductor and Metal Nanocrystals This DNA-based molecular ruler quantitatively measures the steady-state energy and population distribution of plasmon-generated hot carriers in metal nanocrystals. Photo-generated charge carriers, such as plasmon-generated hot electrons and holes,...
Published: 4/29/2026   |   Updated: 4/29/2026   |   Inventor(s): Wei Wei, Yue Hu
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Physical Sciences > Chemistry
Small Molecule Inhibitors Targeting OTUD4-CD73 Interaction for Immune-Cold Tumors
Application This technology introduces small molecule inhibitors, ST80 and Z22, to disrupt the protein-protein interaction (PPI) between OTUD4 and CD73. These inhibitors enhance tumor immunogenicity by reducing CD73 stabilization, improving the immune response in triple-negative breast cancer (TNBC) and other immune-cold tumors. Key Benefits ST80...
Published: 4/10/2026   |   Updated: 11/13/2025   |   Inventor(s): Yong Wan, Yueming Zhu, Ivet Bahar, Anupam Banerjee, Jiyoung Lee
Keywords(s): Drug Target Identification, Immunotherapy, Oncology Treatments, Small Molecule, Therapeutics
Category(s): TechPub Algolia > Drug Discovery
Novel Human Insulin Cα-Peptide as an Antagonist for Islet and Brain Amyloidosis
Summary: The NIA seeks co-development partners and/or licensees for the further development of Cα-peptide as a therapeutic that inhibits islet amyloidosis. Description of Technology: Over 32 million Americans are living with Diabetes and newly diagnosed cases of type 1 and type 2 diabetes is increasing. A defining feature of type 2 diabetes...
Published: 4/24/2026   |   Updated: 8/2/2023   |   Inventor(s): Qing Rong Liu, Min Zhu, Pingbo Zhang, Josephine Earley, Luigi Ferrucci
Keywords(s): Alzheimer’s Disease, Amyloidosis, C-peptide, DIABETES, Egan, insulin, Islet Amyloid Polypeptide, Liu, National Institute on Aging, NIA
Category(s): Collaboration Sought > Licensing, Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Endocrinology
Novel Human Islet Amyloid Polypeptides as Alzheimer’s Disease Biomarkers and Inhibitors of Amyloid Formation
Description of Technology: Over 34 million Americans are living with diabetes. An estimated 6.5 million Americans are living with Alzheimer’s disease (AD) and type 2 diabetes mellites (T2DM). Amyloidosis due to aggregation of amyloid-β is key pathogenic event in AD, whereas aggregation of mature islet amyloid polypeptide (IAPP37) in human...
Published: 4/16/2026   |   Updated: 8/2/2023   |   Inventor(s): Qing Rong Liu, Min Zhu, Josephine Earley
Keywords(s): Ad, Age-Associated Disease, Alzheimer’s Disease, Amyloidosis, Amyloids, Biomarkers, DIABETES, IAPP, Islet Amyloid Polypeptide Isoforms, Liu, National Institute on Aging, NIA, PEPTIDYL
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Therapeutics