Search Results - xianghui+he

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48-Position Custom Deep Well Plate For In Vitro Equilibrium Dialysis at a 1:1 Sample to Buffer Volume Ratio
CDC scientists have developed a new design for a multi-well dialysis microplate for equilibrium dialysis. The unique design accommodates a 1:1 buffer to sample ratio and provides additional room at the base of the well to enable optimal cartridge immersion and analyte diffusion. The microplate is readily adaptable into existing automated analytical...
Published: 4/10/2026   |   Updated: 4/8/2026   |   Inventor(s): Ashley Ribera, Hui Zhou, Hubert Vesper
Keywords(s):  
Category(s): Application > Diagnostics, Application > Research Materials, Collaboration Sought, TherapeuticArea, TherapeuticArea > Endocrinology, TherapeuticArea > Geriatrics, TherapeuticArea > Hematology, TherapeuticArea > Obstetrics/Neo-Natal, TherapeuticArea > Reproductive Health, TherapeuticArea > Urology
Systems and Methods for Concurrent Biochemical Immunoassay and Cellular Traction Force Measurement in Hydrogels
This invention relates to a platform that couples bead-based immunoassays with 3D traction force microscopy (TFM) within a single hydrogel substrate to quantify time-resolved biochemical cues and cell-generated mechanical forces at matched locations. This invention allows researchers to directly test how local molecular cues influence cell mechanics...
Published: 5/1/2026   |   Updated: 3/23/2026   |   Inventor(s): Alex McGhee, Kelvin Pond, A Departmental Work
Keywords(s):  
Category(s): Technology Classifications > Imaging & Optics > Sensors and Detection, Technology Classifications > Engineering & Physical Sciences > Photonics, Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Research Tools > Screening assays
Polymerase-Theta Inhibition for Treating Epstein-Barr Virus (EBV) Cancers and Related Diseases
Proteolysis Targeting Chimeras (PROTACs) Block Microhomology or Theta-Mediated End Joining in Cancer Cells These polymerase theta inhibitors treat Epstein-Barr virus (EBV)-associated cancers and related diseases. EBV cancers are linked to two percent of the global cancer burden and are difficult to treat, demonstrating a strong need for effective...
Published: 4/13/2026   |   Updated: 3/18/2026   |   Inventor(s): Sumita Bhaduri-McIntosh, Michael McIntosh, Guangrong Zheng, Hui Chen
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Therapeutics
Fully Wearable Band for Long-Term Peripheral Ultrasound Neuromodulation in Pain Management
Wearable ultrasound neuromodulation device for peripheral nerve pain relief A wearable ultrasound armband uses a focused piezoelectric transducer and acoustic hydrogel to deliver low-intensity ultrasound pulses to peripheral nerves, noninvasively reducing chronic and neuropathic pain for several hours. Background Peripheral nerve stimulation has...
Published: 3/11/2026   |   Updated: 3/11/2026   |   Inventor(s): Huiliang Wang, William Barrera, Jinmo Jeong, Thomas Wynn, Xiang Qian, QiLiang Chen, Yaoyao Jia, Yiming Han
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices
Student Outcomes & Predictions in Higher Education using Artificial Intelligence (SOPHEA-I )
RPI ID: 2021-021-401 Innovation Summary: A predictive analytics system uses student data to forecast retention rates across academic programs. The model incorporates behavioral, demographic, and performance metrics to identify at-risk students. Machine learning algorithms continuously refine predictions based on new inputs. The system supports institutional...
Published: 3/10/2026   |   Updated: 3/10/2026   |   Inventor(s): Jasmine Yang, Lu Enzhe, Jiarun Li, Yihui Yang, Hui Su, Yifan Liu, Keith Moo-Young
Keywords(s): AI, machine-learning, Student Persistent and success
Category(s): Media, Arts, Science and Technology
Ultrasound-triggered anesthetic drug delivery for on-demand chronic pain management
A nanoparticle-based ultrasound-responsive drug delivery system for precise, controlled, and targeted therapeutic release This technology uses ultrasound-triggered nanoparticles to deliver local anesthetics precisely and safely for pain management, reducing side effects and opioid risks, with potential for targeted delivery of other drugs in cancer,...
Published: 3/10/2026   |   Updated: 2/17/2026   |   Inventor(s): Huiliang Wang, Weilong He, Xi Shi, George Bittner, Cathy Yang, Yanxing Wang, Wenliang Wang, Pengyu Ren
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices
Dark Eye Harvester
This invention involves using an insulated light-proof chamber that allows the harvesting of eyes or another light-sensitive biomaterial without light exposure, allowing visual rhodopsin to regenerate more efficiently. The chamber has a cylindrical shape and is attached to a chest cooler with handles on top to rotate the walls. The chamber has multiple...
Published: 2/9/2026   |   Updated: 2/9/2026   |   Inventor(s): A Departmental Work, Michael Brown
Keywords(s):  
Category(s): Technology Classifications > Engineering & Physical Sciences > Devices & Instrumentation, Technology Classifications > Research Tools
Hollow Capsules Of Nitrogen-doped Porous Carbon-based Electrocatalysts
Advantages High catalytic activity and selectivity for oxygen reduction reaction (ORR) in acidic media, comparable to commercial Pt/C catalysts Atomically dispersed transition metal sites (Fe, Co, Ni, or combinations) coordinated by nitrogen, ensuring efficient and stable catalysis Hollow, porous nitrogen-doped carbon structure with high surface...
Published: 5/11/2026   |   Updated: 2/3/2026   |   Inventor(s): Shengqian Ma, Hui Yang
Keywords(s):  
Category(s): Technology Classifications > Engineering > Chemical Engineering
An Acoustic Device for Large Area Single Cell Trapping and Selective Release (Case No. 2025-047)
Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed an acoustic microfluidic platform that offers a cost-effective and practical approach for handling individual cells at the microscale. Background: Single-cell manipulation is essential for understanding cellular behavior, disease progression, and therapeutic...
Published: 1/13/2026   |   Updated: 1/13/2026   |   Inventor(s): Pei-Yu Chiou, Xiang Zhang
Keywords(s): acoustic microfluidics, acoustic potential wells, acoustics, cell proliferation, cell viability, Diagnostic Platform Technologies (E.G. Microfluidics), diagnostic platforms, Digital Microfluidics, disposable microfluidic platforms, high throughput, high throughput assays, high throughput testing, High-Content Screening, high-throughput cell handling, low-cost fabrication, MEMS, MEMS metasurface, micro-electromechanical systems (MEMS), Microfluidics, Microfluidics And Mem's, Microfluidics Dielectrophoresis, Microfluidics Multi-Band Device, Microfluidics Nanosphere, near-infrared laser, photolithography-free fabrication, research instrumentation, scalable platform, single cell analysis, single cell analysis and testing, Single cell data, single-cell handling, single-cell manipulation, single-cell resolution, single-cell trapping
Category(s): Chemical, Chemical > Chemical Processing & Manufacturing, Chemical > Instrumentation & Analysis, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Diagnostic Markers > Immunology, Diagnostic Markers > Cancer, Life Science Research Tools, Life Science Research Tools > Lab Equipment, Life Science Research Tools > Microfluidics And Mems, Life Science Research Tools > Research Methods, Mechanical, Mechanical > Instrumentation, Platforms, Platforms > Diagnostic Platform Technologies
Performance-enhancing socks for energy-efficient human locomotion
Background Improving the efficiency of human locomotion can enhance endurance, reduce fatigue, and boost athletic performance across a wide range of activities such as walking, running, hiking, and sprinting. These improvements are valuable not only for elite athletes but also for individuals managing age-related declines in mobility or seeking better...
Published: 1/13/2026   |   Updated: 12/4/2025   |   Inventor(s): Owen Beck, Hui Tang
Keywords(s):  
Category(s): Life sciences > Medical technology
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