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Single Use Minimally Invasive Orthopedic Bone Biopsy and Graft Introduction Tray
The Single Use Minimally Invasive Orthopedic Bone Biopsy and Graft Introduction Tool Tray is an all-inclusive, innovative tool tray designed to improve the efficiency and effectiveness of orthopedic macro biopsies through a safe, secure, controlled minimally invasive approach even through normal intact cortical bone. Background: Orthopedic surgeons...
Published: 6/29/2026   |   Updated: 6/25/2026   |   Inventor(s): Timothy Damron
Keywords(s): biopsy, bone, bone filler, bone graft, minimally invasive, orthopedic oncology, orthopedic surgery, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering
A novel SHIP1-selective inhibitor to induce blood cell recovery and stem cell engraftment
A32 is a highly selective small molecule that inhibits the SHIP1 enzyme, boosting blood cell growth factors and potentially improving recovery and immunity after chemotherapy, radiation, or stem cell transplantation, without affecting the related SHIP2 enzyme. Background: Hematopoiesis, the process by which blood cells are formed, is critical for...
Published: 6/29/2026   |   Updated: 6/24/2026   |   Inventor(s): William Kerr, Chiara Pedicone, Denzil Bernard
Keywords(s): bleeding disorders, Blood cell recovery, fungal infection, neutrophils, platelets, stem cell transplants, Technologies
Category(s): Technology Classifications > Therapeutics and Vaccines, Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering
Bi-Directional mTOR Blockade and Companion Biomarkers of Flare and Predictors of Therapeutic Efficacy in SLE
Novel therapeutic intervention targeting mTOR pathways combined with companion biomarkers enables personalized treatment of SLE and its liver complications. Background: Systemic lupus erythematosus (SLE) is a chronic, heterogeneous autoimmune disorder marked by dysregulated immune activity, systemic inflammation, and progressive damage across multiple...
Published: 6/29/2026   |   Updated: 6/23/2026   |   Inventor(s): Andras Perl
Keywords(s): biomarker diagnostics, biomarkers, drug efficacy, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering
CMT-3 nanoformulations for systemic and local administration for inflammation control
The technology introduces innovative telodendrimer nanoformulations of the anti-inflammatory agent CMT-3 that enhance its solubility and bioavailability for effective systemic and local inflammation control. Background: CMT-3 is a potent anti-inflammatory compound with promising therapeutic potential; however, its poor water solubility significantly...
Published: 6/22/2026   |   Updated: 6/21/2026   |   Inventor(s): Juntao Luo, Robert Cooney, Qinghe Meng, Xiaojing Wang, Dandan Guo, Gary Nieman
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering
Reduction of Lipid Accumulation Reverses Aging
Therapeutic strategy to treat age-related cardiovascular disease and restore cardiovascular function through maintenance of lipid homeostasis. Background: Age is a key risk factor for cardiovascular disease such as atherosclerosis, which is characterized by endothelial dysfunction, extracellular matrix remodeling, lipid accumulation, chronic inflammation...
Published: 6/19/2026   |   Updated: 6/15/2026   |   Inventor(s): Stylianos Andreadis, Yulun Wu, Pihu Mehrotra
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Healthcare, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Therapeutics and Vaccines
Bio Roll-Up: Material and Process Improvements
Bio Roll-Up is a hydrogel technology that creates flat cell sheets which can be triggered to roll into 3D shapes, using layered polymers and additives like gelatin for improved cell attachment, enabling precise, biomimetic tissue engineering applications. Background: Tissue engineering and regenerative medicine are rapidly advancing fields that seek...
Published: 6/12/2026   |   Updated: 6/12/2026   |   Inventor(s): Robert Brainard, Ledina Banushllari
Keywords(s): Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering
Fast, Background-free Detection of Nucleic Acid Sequences Using DNA Nanoswitches
This technology introduces DNA-based "nanoswitches"—innovative nanostructures that enable precise and efficient detection of target analytes through conformational changes. Background: Accurate detection of specific molecules, such as DNA sequences or other analytes, is fundamental in medical diagnostics, environmental monitoring,...
Published: 5/6/2026   |   Updated: 5/5/2026   |   Inventor(s): Kenneth Halvorsen, Wesley Wong, Arun Richard Chandrasekaran
Keywords(s):  
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering
Bruton's Tyrosine Kinase as Anti-Cancer Drug Target
This technology identifies Bruton's Tyrosine Kinase (BTK) as a novel target in breast cancer therapy and provides methods for treatment and diagnosis by inhibiting a specific BTK variant. Background: Protein tyrosine kinases (PTKs) are essential enzymes involved in cellular communication and regulation, often playing a significant role in cancer...
Published: 5/5/2026   |   Updated: 5/4/2026   |   Inventor(s): Douglas Conklin, Antonis Kourtidis, Cheryl Eifert
Keywords(s): breast cancer, cancer, TAF, Technologies, therapeutic targets
Category(s): Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Biomedical Science and Engineering, Campus > University at Albany
Electromotive anti fibrotic substance administration for fibrotic diseases
This technology uses a gentle electrical current to deliver antifibrotic drugs like collagenase directly into fibrotic tissues, such as the bladder wall, enabling noninvasive, targeted treatment of fibrosis and improving tissue function without surgery. Background: Fibrosis of the bladder wall, particularly in the context of neurogenic bladder, represents...
Published: 4/28/2026   |   Updated: 4/28/2026   |   Inventor(s): Jeffrey Villanueva
Keywords(s): fibrosis, fibrous materials, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering
β-Catenin agonists recapitulate the protective effects of genetic stabilization
This technology uses drugs that stabilize β-catenin to boost protective immune cells in the lungs, reducing damage from pulmonary hemorrhage and inflammatory lung diseases by activating a novel immunomodulatory pathway. Background: Pulmonary hemorrhage and other inflammatory lung diseases represent significant clinical challenges due to their...
Published: 4/22/2026   |   Updated: 3/24/2026   |   Inventor(s): Mobin Karimi
Keywords(s): gene coding, gene therapies, gene therapy, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Biomedical Science and Engineering
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