Search Results - meng+meng

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Lipid nanoparticles for lung-targeted mRNA delivery
This technology is a new lipid nanoparticle system that can safely, specifically, and efficiently deliver mRNA to a patient’s lungs. Background: Therapeutics that deliver mRNA to a patient’s lungs offer significant potential for treating a broad spectrum of lung diseases. However, specifically and efficiently delivering mRNA to lung tissue...
Published: 6/22/2026   |   Updated: 6/21/2026   |   Inventor(s): Yamin Li, David Popoola, Zhi Cao, Yuqin Men
Keywords(s): biomaterials, chemistry, drug delivery, gene therapy, nanoparticle drug delivery, RNA, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Therapeutics and Vaccines
CMT-3 nanoformulations for systemic and local administration for inflammation control
The technology introduces innovative telodendrimer nanoformulations of the anti-inflammatory agent CMT-3 that enhance its solubility and bioavailability for effective systemic and local inflammation control. Background: CMT-3 is a potent anti-inflammatory compound with promising therapeutic potential; however, its poor water solubility significantly...
Published: 6/22/2026   |   Updated: 6/21/2026   |   Inventor(s): Juntao Luo, Robert Cooney, Qinghe Meng, Xiaojing Wang, Dandan Guo, Gary Nieman
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering
Pancreas-specific mRNA delivery enabled by sulfonium lipid nanoparticles
This technology presents a novel class of lipid nanoparticles engineered for targeted delivery of mRNA specifically to the pancreas following systemic administration. Background: Effective delivery of RNA therapeutics to specific organs remains a significant challenge in biomedical research. The pancreas, in particular, has been a difficult target...
Published: 6/12/2026   |   Updated: 6/11/2026   |   Inventor(s): Yamin Li, Yuqin Men
Keywords(s): mRNA, nanoparticle-enhanced delivery, nanoparticles, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Drug Delivery
A lung-targeting britannin-lipid nanoparticle formulation and use thereof
This technology is a novel lung-targeting britannin-lipid nanoparticle formulation designed to effectively treat acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) by inhibiting lung inflammation. Background: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are severe lung conditions characterized by intense...
Published: 6/12/2026   |   Updated: 6/11/2026   |   Inventor(s): Yamin Li, Qinghe Meng, Daping Fan
Keywords(s): acute lung injury, drug delivery, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Drug Delivery
Bio-polyol fractionation and formulation strategies for bio-based polyurethane materials
This technology uses a room-temperature solvent process to separate and blend lignin and other bio-polyols, enabling the production of customizable, high-performance, bio-based polyurethane foams, coatings, and adhesives as sustainable alternatives to petroleum-based materials. Background: The field of polyurethane production has traditionally relied...
Published: 5/14/2026   |   Updated: 4/1/2026   |   Inventor(s): Chang Geun Yoo, Soyeon Jeong, Charles Cai, Xianzhi Meng, Arthur Ragauskas, Mairui Zhang
Keywords(s): biorefining, green chemistry, Sustainability, Technologies
Category(s): Campus > SUNY Environmental Science & Forestry, Technology Classifications > Environment
Lung-targeting mRNA-lipid nanoparticles for the treatment of acute lung injury
This technology uses lung-targeting lipid nanoparticles to deliver IL-10 mRNA directly to the lungs, reducing inflammation and injury in conditions like acute lung injury and ARDS, while minimizing side effects and improving treatment effectiveness. Background: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are severe, life-threatening...
Published: 3/19/2026   |   Updated: 3/19/2026   |   Inventor(s): Yamin Li, Yuqin Men, Qinghe Meng, Robert Cooney
Keywords(s): anti-inflammatory therapeutic, drug delivery, lipids, mRNA, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Healthcare
Lung-targeting mRNA-lipid nanoparticles for the treatment of acute lung injury
This technology uses lung-targeting lipid nanoparticles to deliver IL-10 mRNA directly to the lungs, reducing inflammation and injury in conditions like acute lung injury and ARDS, while minimizing side effects and improving treatment effectiveness. Background: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are severe, life-threatening...
Published: 3/19/2026   |   Updated: 3/19/2026   |   Inventor(s): Yamin Li, Yuqin Men, Qinghe Meng, Robert Cooney
Keywords(s): anti-inflammatory therapeutic, drug delivery, lipids, mRNA, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Healthcare
Lipid nanoparticles for targeted delivery of therapeutic agents in acute lung injury
This technology uses lung-targeting lipid nanoparticles to deliver a combination of anti-inflammatory and immune-modulating drugs directly to the lungs, offering a more effective and targeted treatment for acute lung injury and acute respiratory distress syndrome. Background: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS)...
Published: 4/2/2026   |   Updated: 1/15/2026   |   Inventor(s): Yamin Li, Yuqin Men, Robert Cooney, Qinghe Meng
Keywords(s): acute lung injury, anti-inflammatory therapeutic, drug delivery, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Drug Delivery
Lipid nanoparticles for targeted delivery of therapeutic agents in acute lung injury
This technology uses lung-targeting lipid nanoparticles to deliver a combination of anti-inflammatory and immune-modulating drugs directly to the lungs, offering a more effective and targeted treatment for acute lung injury and acute respiratory distress syndrome. Background: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS)...
Published: 4/2/2026   |   Updated: 1/15/2026   |   Inventor(s): Yamin Li, Yuqin Men, Robert Cooney, Qinghe Meng
Keywords(s): acute lung injury, anti-inflammatory therapeutic, drug delivery, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Drug Delivery
Sulfonium Lipid Nanoparticles for Intranasal mRNA Delivery to Lung Epithelial and Immune Cells
This technology uses specially designed sulfonium lipid nanoparticles to deliver mRNA directly to lung cells through the nose, offering a non-invasive, more effective and targeted treatment for pulmonary diseases like asthma and cystic fibrosis. Background: The field of pulmonary medicine faces significant challenges in the treatment of diseases...
Published: 6/3/2026   |   Updated: 1/9/2026   |   Inventor(s): Yamin Li, Yuqin Men
Keywords(s): active pharmaceutical ingredient, chemicals, drug delivery, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Delivery
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