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Novel ZnO Nanowire-Based Hybrid Nanocarrier for Cancer Drug and Gene Delivery

This invention relates to a novel tri-component nanocomposite system comprising commercially available zinc oxide nanowires (ZnO NWs) functionalized to simultaneously deliver both small-molecule drugs and genetic material to cancer cells. This hybrid nanocarrier platform addresses critical limitations of current cancer therapies, including poor tumor...

Published: 5/6/2026 | Updated: 5/6/2026 | Inventor(s): Prashant Sharma, Mario Otto

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences > Drug Delivery, Technology Classifications > Life Sciences > Therapeutics

Multi-Targeted Kinase Inhibitors Towards AML and Other Cancers

This invention relates to small-molecule compounds that are potential therapeutics for Acute Myeloid Leukemia (AML), specifically AML with the FMS-like tyrosine kinase 3 (FLT3) mutation. The compounds also show activity versus Abl kinases, platelet-derived growth factor receptor (PDGFR), and the dual-specificity tyrosine regulated/Cdc2-like (DYRK/CLK)...

Published: 5/6/2026 | Updated: 5/6/2026 | Inventor(s): Christopher Hulme, Alessandra Fistrovich, Samantha Rokey, Aidan McMahon, Timothy Chavez, Jennifer Carew

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics

Chimeric Inhibitors

Chimeric PARP/NAMPT inhibitors have been designed to be phosphoribosylated by NAMPT (nicotinamide phosphoribosyltransferase). This modification enriches the cytotoxic adducts held within cancer cells that overexpress NAMPT and significantly increases the safety and efficacy of PARP inhibition, minimizes resistance, and promotes further cancer cell death....

Published: 3/4/2026 | Updated: 3/4/2026 | Inventor(s): Gregory Thatcher, Jiqiang Fu, Ganga Reddy Velma

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Oncology

CRISPR-Cas13-Based Isothermal Assay for Multiplex Detection of Circulating MicroRNAs from Small-Volume Blood Samples

This invention relates to the field of molecular diagnostics and nucleic acid detection. In particular, it concerns an isothermal assay platform for the multiplex detection of circulating microRNAs (miRNAs) in small-volume blood samples. The platform is useful for early detection, screening, or monitoring of diseases such as cancer and other conditions. Background:...

Published: 5/6/2026 | Updated: 2/16/2026 | Inventor(s): Ravi Goyal

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Category(s): Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Medical Devices > Diagnostic, Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Healthcare Portfolios > Blood & Lymphatic Disease

Simultaneous Bilateral Breast Imaging without Compression using Offset Detector

This invention involves an upright cone-beam breast computed tomography (CT) designed to image two breasts simultaneously with high resolution. The design prevents patients from having to reposition their bodies between images. Additionally, this invention builds on the deep learning algorithm for breast CT image reconstruction. Background: Present...

Published: 5/1/2026 | Updated: 2/4/2026 | Inventor(s): Hsin Wu Tseng, Srinivasan Vedantham

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Healthcare Portfolios > Radiology, Technology Classifications > Imaging & Optics > Medical Imaging, Technology Classifications > Life Sciences > Diagnostics

Inhibition of Metastasis in Triple Negative Breast Cancer

This invention uses a therapeutic peptide sequence that inhibits breast cancer metastasis by activating natural killer (NK) cells against breast cancer cells. This inhibitor can be used to treat triple-negative breast cancer metastasis, associated with excess epidermal growth factor receptor (EGRF) which is overexpressed and amplified in 60% of triple-negative...

Published: 1/21/2026 | Updated: 1/21/2026 | Inventor(s): Joyce Schroeder

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Therapeutic Target of Ewing Sarcoma by G-Quadruplex Binding Compound

This innovation identified lead molecules that target specific nucleic acid structures involved with forming G-Quadruplex structures. These G-Quadruplex structures are a highly stable nucleic acid fold with planar stacks of guanine tetrads which regulate genome stability, transcription, and telomere maintenance. This innovation details a therapeutic...

Published: 3/12/2026 | Updated: 1/6/2026 | Inventor(s): Jacob Schwartz, Haining Zhu, Ajibola Adelekun, Valery Thompson

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Oncology

Secretory Acid Sphingomyelinase Activity as a Diagnostic Marker in Colorectal Cancer

This invention utilizes the activity of secretory acid sphingomyelinase (S-SMase) in patient serum as a biomarker for the early or enhanced detection of colorectal neoplasia, including colorectal cancer (CRC). Background: Colorectal cancer (CRC) is one of the most common cancers worldwide, ranking third in incidence and second in cancer-related deaths...

Published: 9/22/2025 | Updated: 9/22/2025 | Inventor(s): Ashley Snider, Nathan Ellis, Justin Snider, Peter Lance

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Diagnostics

Lipid-Based Diagnostic for Minimally-Invasive Screening and Early Detection of Gynecologic Cancer

This invention is a non-invasive diagnostic for the screening and early detection of gynecologic cancers, including endometrial, cervical, and ovarian cancer, based on a lipid panel. It analyzes cervicovaginal lavages for key biomarkers that could ultimately be used a screening technology as a part of a well-woman exam to assess the risk of gynecologic...

Published: 5/6/2026 | Updated: 9/22/2025 | Inventor(s): Melissa Herbst-Kralovetz, Pawel Laniewski

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Category(s): Technology Classifications > Healthcare Portfolios > Women's Health, Technology Classifications > Healthcare Portfolios > Reproductive Health: Obstetrics & Gynecology, Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics

Biomarker for the Classification of Melanocytic Neoplasms

This invention relates to potential transcriptomic biomarkers using gene- or protein-level expression of individual or a combination of the 23 genes/proteins to accurately differentiate between low-risk, benign from high-risk, malignant melanocytic neoplasms. This approach aims to improve the accuracy of melanoma diagnosis and reduce diagnostic uncertainty. Background:...

Published: 10/15/2025 | Updated: 9/15/2025 | Inventor(s): Karen Hastings, Elizabeth Borden, Bonnie LaFleur

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Life Sciences > Diagnostics

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