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Topical Minocycline Ointment Suppresses Allergic Skin Responses
This technology presents a topical minocycline ointment formulated to effectively suppress allergic skin responses and reduce inflammation associated with allergic reactions. Background: Allergic skin reactions, such as hives, rashes, and inflammation caused by insect bites or contact with allergens, present common dermatological challenges that...
Published: 6/22/2026   |   Updated: 6/16/2026   |   Inventor(s): Rauno Joks, Helen Durkin (Deceased)
Keywords(s):  
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Healthcare
Suppression of histamine and allergen induced itch and swelling with topical minocycline cream
This invention presents a topical 2% minocycline cream that significantly reduces histamine- and allergen-induced itching and swelling, offering a novel non-steroidal treatment for allergic skin reactions. Background: Allergic skin reactions, characterized by itching and swelling, affect many individuals and are commonly managed with steroid-based...
Published: 6/22/2026   |   Updated: 6/16/2026   |   Inventor(s): Rauno Joks
Keywords(s): Technologies
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Healthcare
Reduction of Lipid Accumulation Reverses Aging
Therapeutic strategy to treat age-related cardiovascular disease and restore cardiovascular function through maintenance of lipid homeostasis. Background: Age is a key risk factor for cardiovascular disease such as atherosclerosis, which is characterized by endothelial dysfunction, extracellular matrix remodeling, lipid accumulation, chronic inflammation...
Published: 6/19/2026   |   Updated: 6/15/2026   |   Inventor(s): Stylianos Andreadis, Yulun Wu, Pihu Mehrotra
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Healthcare, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Therapeutics and Vaccines
Developing a new mechanism-based method to treat behavioral variant frontotemporal dementia
This technology offers a novel, mechanism-based therapeutic method using oxytocin and specific compounds to treat social-affective deficits in behavioral variant frontotemporal dementia (bvFTD). Background: Behavioral variant frontotemporal dementia (bvFTD) is a prevalent form of dementia characterized by severe social and emotional impairments,...
Published: 3/30/2026   |   Updated: 3/30/2026   |   Inventor(s): Wei-Dong Yao
Keywords(s): dementia, electrophysiology, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Healthcare, Technology Classifications > Therapeutics and Vaccines
Lung-targeting mRNA-lipid nanoparticles for the treatment of acute lung injury
This technology uses lung-targeting lipid nanoparticles to deliver IL-10 mRNA directly to the lungs, reducing inflammation and injury in conditions like acute lung injury and ARDS, while minimizing side effects and improving treatment effectiveness. Background: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are severe, life-threatening...
Published: 3/19/2026   |   Updated: 3/19/2026   |   Inventor(s): Yamin Li, Yuqin Men, Qinghe Meng, Robert Cooney
Keywords(s): anti-inflammatory therapeutic, drug delivery, lipids, mRNA, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Healthcare
Self-delivery USP10 siRNA to promote regenerative healing-new IP
This technology employs an engineered self-delivering siRNA to selectively reduce USP10 protein levels in tissues, thereby promoting regenerative healing and suppressing pathological scarring. Preclinical studies in the eye demonstrate a favorable safety profile and robust efficacy, supporting the potential of this approach for treating fibrotic disease...
Published: 3/18/2026   |   Updated: 3/18/2026   |   Inventor(s): Audrey Bernstein, Sean McCauley, Alexey Wolfson, Tere Williams
Keywords(s): fibrosis, opthalmology, scarring, siRNA, skin diseases, Technologies
Category(s): Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Campus > Upstate Medical University
Diabetic Foot Examiner
This technology enables diabetic patients to detect foot ulcers easily and effectively at home. Background: Diabetic foot ulcers are a significant health problem (15% baseline probability) in the growing diabetic population. Foot ulcers can become infected and lead to hospitalization or even amputation. The best way to address this disease is through...
Published: 3/13/2026   |   Updated: 3/12/2026   |   Inventor(s): Ronald Miller
Keywords(s): artificial intelligence, diabetes, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Healthcare
3D-Printed Theranostic Dose Caddy
This technology enables safer administration of radioligand therapies, allowing for healthier, lower radiation doses to both patients and administering staff. Background: At present, there are two FDA-approved radioligand therapies for broad use in cancer treatment: Lutathera (177Lutetium DOTATATE) and Pluvicto (177Lutetium Vipivotide Tetraxetan)....
Published: 3/13/2026   |   Updated: 3/12/2026   |   Inventor(s): David Lubin, David Feiglin, Kurtis Wilson, Leen Alkukhun, Garrett Depalma, Kent Ogden, Mary McGrath, Paul Depew, Zohaib Khan, Meghan Stanton
Keywords(s): 3D printing, cancer therapy, radiology, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Healthcare
Modular Hybrid Simulator (Endovascular Flow model with embedded sensors for operative feedback) powered by 3D auto segmentation software for Endovascular Modeling and Flow Model additions.
The Modular Hybrid Simulator is an advanced training platform for endovascular procedures, combining patient-specific 3D modeling with real-time operative feedback to enhance learning and procedural planning. Background: Endovascular training currently faces challenges such as inconsistent learning curves among trainees and the limitations of existing...
Published: 3/3/2026   |   Updated: 3/2/2026   |   Inventor(s): Hesham Masoud
Keywords(s): Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Healthcare
Ultrasonic Transmission System with Modular Cavitation-Enhancing Wire
This device uses ultrasonic vibrations delivered through a specialized wire to safely and efficiently clear blockages or remove implants from medical tubes, offering a non-invasive, customizable solution for maintaining and treating tube obstructions in healthcare settings. Background: Nephrostomy tubes and other indwelling medical devices are critical...
Published: 3/26/2026   |   Updated: 3/2/2026   |   Inventor(s): Alexander Collins, Scott Wiener
Keywords(s): modular instrument, Technologies
Category(s): Campus > Upstate Medical University, Technology Classifications > Healthcare
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