Search Results - rauno+joks

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Topical Minocycline Ointment Suppresses Allergic Skin Responses

This technology presents a topical minocycline ointment formulated to effectively suppress allergic skin responses and reduce inflammation associated with allergic reactions. Background: Allergic skin reactions, such as hives, rashes, and inflammation caused by insect bites or contact with allergens, present common dermatological challenges that...

Published: 6/22/2026 | Updated: 6/16/2026 | Inventor(s): Rauno Joks, Helen Durkin (Deceased)

Keywords(s):

Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Healthcare

Suppression of histamine and allergen induced itch and swelling with topical minocycline cream

This invention presents a topical 2% minocycline cream that significantly reduces histamine- and allergen-induced itching and swelling, offering a novel non-steroidal treatment for allergic skin reactions. Background: Allergic skin reactions, characterized by itching and swelling, affect many individuals and are commonly managed with steroid-based...

Published: 6/22/2026 | Updated: 6/16/2026 | Inventor(s): Rauno Joks

Keywords(s): Technologies

Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Healthcare

Use of Blood Nitric Oxide Responses as a Biomarker of Obesity and its Associated Conditions, including Allergy and Asthma

This technology offers a novel method for identifying individuals at increased risk for systemic inflammatory disorders, such as asthma, by measuring intracellular nitric oxide synthase expression in specific immune cells. Background: Asthma and other systemic inflammatory disorders often present challenges in effective diagnosis and management due...

Published: 6/12/2026 | Updated: 6/12/2026 | Inventor(s): Rauno Joks, Maja Nowakowski, Helen Durkin (Deceased)

Keywords(s): Technologies

Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Screens and Assays

Suppressive Molecules of Diseases with Altered IgE Regulation

Provides a new platform for the development of diseases associated with abnormal regulation of immunoglobulin E (IgE). Background: Previous research has demonstrated that congeners of tetracycline, minocycline, and doxycycline suppress asthmatic symptoms in vivo, and immunoglobulin E (IgE) from asthmatics in vitro in a dose-dependent manner. In theory,...

Published: 1/30/2026 | Updated: 5/13/2025 | Inventor(s): Helen Durkin (Deceased), Martin Bluth, Rauno Joks, Tamar Smith-Norowitz

Keywords(s): allergy, asthma, atopy, immunoglobulin E (IgE)

Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Biomedical Science and Engineering