Search Results - platforms+%3e+drug+delivery

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Injectable Nanocomposite Hydrogel for Sustained and Targeted Therapeutic Delivery for Disease Treatment and Tissue Regeneration (UCLA Case No. 2026-212)
Contact UCLA Technology Development Group if you are interested in discussing this innovation. More information available soon.
Published: 6/10/2026   |   Updated: 6/10/2026   |   Inventor(s): Nasim Annabi
Keywords(s):  
Category(s): Materials > Nanotechnology, Platforms > Drug Delivery
Gene Editing of Monogenic Disorders in Human Hematopoietic Stem Cells
Case 2018-372Researchers at the UCLA Department of Microbiology, Immunology & Molecular Genetics have developed novel methods to achieve efficient, precise gene integration and effective expression of cDNA cassettes to express normal versions of genes in hematopoietic stem cells.BACKGROUNDHematopoietic stem cells (HSCs) have great therapeutic potential...
Published: 6/3/2026   |   Updated: 6/3/2026   |   Inventor(s): Donald Kohn, Caroline Kuo, Zulema Romero Garcia, Roger Hollis
Keywords(s): Drug Delivery, Gene Editing Systems, Gene Therapy, Life Science Research Tools
Category(s): Platforms > Drug Delivery, Therapeutics > Gene Therapy And Editing, Life Science Research Tools
In Cellulo Syntheses of Targeting-Ligand-Conjugatable, RNA-Specific, Enveloped Virus-Like Particles (UCLA Case No. 2025-159)
Contact UCLA Technology Development Group to learn more. More info available soon.
Published: 6/16/2026   |   Updated: 6/2/2026   |   Inventor(s): William Gelbart
Keywords(s):  
Category(s): Platforms > Drug Delivery, Therapeutics > Gene Therapy And Editing, Life Science Research Tools > Plasmids/Vectors
Highly Miniaturized Closed-Loop Biosensing and Drug Delivery (Case No. 2025-276)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed an implantable closed-loop system that integrates electrochemical biosensing, wireless signal transmission, and programmable drug release. Background: Conventional disease management systems rely on single-point measurements and discrete interval drug...
Published: 2/5/2026   |   Updated: 2/5/2026   |   Inventor(s): Aydin Babakhani, Iman Habibagahi, Hamid Jafarisharemi, Roshan Mathews
Keywords(s): biomedical implantation, biomedical sensors, Drug Delivery, Drug monitoring, Implant (Medicine), implantable sensors, Medical Device, minimally invasive drug delivery systems, on-demand drug delivery, personalized dose assessment, Smart medical device, Therapeutics, wearable, wearable electronics, wearable medical device, wearable medical devices, wearable sensors, wearable sensors for health, Wireless, wireless communication
Category(s): Life Science Research Tools, Electrical, Medical Devices, Platforms > Diagnostic Platform Technologies, Platforms > Drug Delivery, Platforms
In Cellulo Synthesis of mRNA-Specific Stoichiometrically-Precise Virus-Like Particles (UCLA Case No. 2024-056)
UCLA researchers from the Department of Chemistry and Biochemistry have developed a novel virus-like particle (VLP) platform for the encapsulation of mRNA for efficient therapeutic delivery. BACKGROUND: Messenger RNA (mRNA) technologies have emerged as powerful therapeutics in vaccines and gene therapies. While traditional methods of mRNA therapeutics...
Published: 12/8/2025   |   Updated: 12/8/2025   |   Inventor(s): William Gelbart
Keywords(s):  
Category(s): Therapeutics > Vaccines, Platforms > Drug Delivery, Therapeutics > Gene Therapy And Editing, Materials > Nanotechnology
Nanoparticle & dsDNA Toolkit for Decreased Toxicity and Gene Editing of Epithelial Stem Cells via Epithelial Disruption (UCLA Case No. 2023-205/209) -- for Cystic Fibrosis and other genetic diseases
UCLA researchers in the Department of Pediatrics, Hematology/ Oncology have constructed a nanoparticle toolkit for increased integration and reduced toxicity for gene therapies that treat debilitating diseases such as Cystic Fibrosis and other critical genetic diseases. BACKGROUND: Gene therapies are the forefront of therapeutic advancements as a one-off...
Published: 12/1/2025   |   Updated: 12/1/2025   |   Inventor(s): Steven Jonas, Brigitte Gomperts, Donald Kohn
Keywords(s):  
Category(s): Therapeutics > Gene Therapy And Editing, Platforms > Drug Delivery
Hyperbranched Polyglycerol Encapsulated Proteins for Oral Protein Delivery (Case No. 2012-425)
Patent Abstract: Methods for modifying therapeutic agents such as therapeutic biomolecules, such as proteins for improved oral, rectal or transmucosal delivery, as well as compositions made using such methods and methods of administering such compositions to a subject, are disclosed. Specifically, the therapeutic agents are conjugated to hyperbranched...
Published: 12/1/2025   |   Updated: 12/1/2025   |   Inventor(s): Yunfeng Lu, Juanjuan Du, Jie Li, Yang Liu
Keywords(s):  
Category(s): Platforms > Drug Delivery
Pancreas Cancer Immunotherapy using Cationic Lipid and Polymer Nanocarriers for co-delivery of KRAS Neoantigens and STING or other immunomodulators to boost the Cancer Immunity Cycle and Treat Liver Metastasis (UCLA Case No. 2024-076)
UCLA researchers have developed a translational immunotherapy platform that leverages nanoparticle-based delivery of tumor-associated signals and immune-stimulatory molecules to drive localized immune activation in metastatic pancreatic cancer. This approach is designed to initiate de novo immune priming and recondition the tumor microenvironment in...
Published: 10/29/2025   |   Updated: 10/29/2025   |   Inventor(s): Andre Nel
Keywords(s):  
Category(s): Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy, Therapeutics > Vaccines, Platforms > Drug Delivery
Mucus Targeting Particles (MTPs) Technology for Sustained Drug Delivery Applications (UCLA Case No. 2020-809)
UCLA researchers in the Department of Chemical and Biomolecular Engineering have developed a robust nanoparticle technology for effective, sustained-release ocular drug delivery. BACKGROUND: Topically applied therapeutics are the common mode of delivery for treating ocular diseases, ranging from chronic conditions like glaucoma to acute inflammation...
Published: 10/24/2025   |   Updated: 10/24/2025   |   Inventor(s): Nasim Annabi, Shima Gholizadeh, Reza Dana
Keywords(s):  
Category(s): Therapeutics > Ophthalmology, Materials > Nanotechnology, Platforms > Drug Delivery
Synthetic Cannabinoid WIN 55,212-2 Increased the Cytotoxicity of NK Cells and IFN-gamma Secretion Ability of Immune Cells in Humanized BLT Mouse Model (UCLA Case No. 2022-281)
UCLA researchers in the School of Dentistry have developed novel strategies synergizing the anti-tumor effects of a synthetic cannabinoid, cytokine, and probiotic bacteria to augments NK cell mediated functions and target a wide variety of cancers and viral infections. BACKGROUND: Interest in the use of synthetic cannabinoids for the treatment of disease...
Published: 10/23/2025   |   Updated: 10/23/2025   |   Inventor(s): Anahid Jewett
Keywords(s):  
Category(s): Platforms > Drug Delivery, Therapeutics > Oncology > Oncology Immunotherapy
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