Search Results - diagnostic+markers+%3e+targets+and+assays

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Swabseq Universal Pathogen Diagnostic Platform (Case No. 2026-121)
Summary: UCLA researchers in the Department of Computer Science have developed a next-generation universal pathogen diagnostic platform combining scalable genomic sequencing, simplified laboratory workflows, and integrated logistics infrastructure to enable rapid, low-cost, high-throughput infectious disease detection. Background: The rise of pathogen-specific...
Published: 6/5/2026   |   Updated: 6/5/2026   |   Inventor(s): Eleazar Eskin, Valerie Arboleda, Chongyuan Luo, Taryn Jakub, Traci Toy
Keywords(s): AI-guided diagnostics, Assay, Computer-Aided Diagnosis, COVID-19, Diagnostic Markers & Platforms, diagnostic platforms, Diagnostic Test, diagnostics, Infectious Diseases, Infrastructure, Medical diagnostics, metagenomic diagnostic platform, Pathogen, platform technology, scalable platform
Category(s): Therapeutics > Infectious Diseases, Therapeutics > Infectious Diseases > COVID, Software & Algorithms > Digital Health, Software & Algorithms, Platforms > Diagnostic Platform Technologies, Platforms, Diagnostic Markers, Diagnostic Markers > Targets And Assays
Enzyme-Based Method for the Amplified Detection of Molecules on Particles (Case No. 2026-130)
Summary: UCLA researchers in the Department of Bioengineering have developed a novel enzyme-based particle platform that enables amplified molecular detection in fully aqueous systems for sensitive, multiplexed analysis of low-abundance analytes. Background: The detection of molecules and determination of enzymatic activity are foundational across...
Published: 6/15/2026   |   Updated: 6/5/2026   |   Inventor(s): Alyssa Arnheim, Dino Di Carlo
Keywords(s): Antibody, Aptamers, Assay, barcode, Biomarker, Biosensor, Diagnostic Markers & Platforms, Diagnostic Platform Technologies (E.G. Microfluidics), Drug Discovery, ELISA, enzyme functionalization, Enzyme Substrate (Biology), Flow Cytometry, Fluorescence, High-Throughput Screening, hydrogel, Immunoassay, Medical diagnostics, microparticles, Molecular Biology, multiplexed analysis, multiplexing, Nucleic Acids, protein, Signal-To-Noise Ratio
Category(s): Diagnostic Markers > Targets And Assays, Diagnostic Markers, Platforms > Diagnostic Platform Technologies, Chemical > Chemical Sensors, Life Science Research Tools > Antibodies
Novel Biomarkers for Sanfilippo Syndrome (UCLA Case No. 2024-150)
UCLA researchers from the Department of Neurology have identified novel biomarkers of Sanfilippo Syndrome, leading to potential minimally invasive methods to detect Sanfilippo Syndrome and assess clinical trial outcomes. More information to follow. Contact UCLA Technology Development Group if you would like to learn more in the meantime.
Published: 6/3/2026   |   Updated: 6/3/2026   |   Inventor(s): Gal Bitan
Keywords(s):  
Category(s): Therapeutics > CNS and Neurology, Therapeutics > Metabolism And Endocrinology, Diagnostic Markers > Targets And Assays
A Novel Biomarker and Therapeutic Target for Atrial Fibrillation in Humans (UCLA Case No. 2024-041)
UCLA researchers at the Geffen School of Medicine have identified a novel biomarker and therapeutic target for early diagnosis and treatment of post-operative atrial fibrillation. BACKGROUND: Post-operative atrial fibrillation (POAF) is a common complication following cardiac surgery, affecting 30-50% of patients. Patients who develop POAF have an...
Published: 3/26/2026   |   Updated: 3/26/2026   |   Inventor(s): Thomas Vondriska, Matthew Fischer
Keywords(s):  
Category(s): Diagnostic Markers > Targets And Assays, Platforms > Diagnostic Platform Technologies, Therapeutics > Cardiovascular
DNA Methylation Biomarkers to Predict Chronic Lung Allograft Dysfunction (UCLA Case No. 2025-9A0)
UCLA researchers in the Department of Medicine have developed a logistic regression model using DNA methylation biomarkers that enables early, noninvasive prediction of chronic lung allograft dysfunction up to two years before clinical disease onset. BACKGROUND: Chronic lung allograft dysfunction (CLAD) is the leading cause of long-term graft failure...
Published: 2/25/2026   |   Updated: 2/25/2026   |   Inventor(s): Joanna Schaenman
Keywords(s):  
Category(s): Diagnostic Markers > Targets And Assays, Diagnostic Markers > Immunology, Therapeutics > Respiratory And Pulmonary, Software & Algorithms > Artificial Intelligence & Machine Learning, Software & Algorithms > Bioinformatics, Software & Algorithms > Statistical Models
Compositions and Methods to Modulate MAVS-Mediated Immunity (UCLA Case No. 2026-096)
UCLA researchers in the Department of Microbiology, Immunology, and Molecular Genetics have developed methods to target TOM70, a mitochondrial outer membrane protein, to selectively modulate innate immune signaling and control pathological or protective immune responses across a range of clinical conditions. BACKGROUND: Innate immune detection of viral...
Published: 2/18/2026   |   Updated: 2/18/2026   |   Inventor(s): Lena Pernas
Keywords(s):  
Category(s): Diagnostic Markers > Targets And Assays, Diagnostic Markers > Immunology, Diagnostic Markers > Cancer, Platforms > Diagnostic Platform Technologies, Therapeutics > Oncology, Therapeutics > Infectious Diseases, Therapeutics > Immunology And Immunotherapy, Therapeutics > Inflammation And Inflammatory Diseases, Therapeutics > Autoimmune, Therapeutics > Vaccines
An Acoustic Device for Large Area Single Cell Trapping and Selective Release (Case No. 2025-047)
Summary: UCLA researchers in the Department of Mechanical and Aerospace Engineering have developed an acoustic microfluidic platform that offers a cost-effective and practical approach for handling individual cells at the microscale. Background: Single-cell manipulation is essential for understanding cellular behavior, disease progression, and therapeutic...
Published: 1/13/2026   |   Updated: 1/13/2026   |   Inventor(s): Pei-Yu Chiou, Xiang Zhang
Keywords(s): acoustic microfluidics, acoustic potential wells, acoustics, cell proliferation, cell viability, Diagnostic Platform Technologies (E.G. Microfluidics), diagnostic platforms, Digital Microfluidics, disposable microfluidic platforms, high throughput, high throughput assays, high throughput testing, High-Content Screening, high-throughput cell handling, low-cost fabrication, MEMS, MEMS metasurface, micro-electromechanical systems (MEMS), Microfluidics, Microfluidics And Mem's, Microfluidics Dielectrophoresis, Microfluidics Multi-Band Device, Microfluidics Nanosphere, near-infrared laser, photolithography-free fabrication, research instrumentation, scalable platform, single cell analysis, single cell analysis and testing, Single cell data, single-cell handling, single-cell manipulation, single-cell resolution, single-cell trapping
Category(s): Chemical, Chemical > Chemical Processing & Manufacturing, Chemical > Instrumentation & Analysis, Diagnostic Markers, Diagnostic Markers > Targets And Assays, Diagnostic Markers > Immunology, Diagnostic Markers > Cancer, Life Science Research Tools, Life Science Research Tools > Lab Equipment, Life Science Research Tools > Microfluidics And Mems, Life Science Research Tools > Research Methods, Mechanical, Mechanical > Instrumentation, Platforms, Platforms > Diagnostic Platform Technologies
Oral-Gut-Brain Axis Virome/Microbiome for Periodontitis, Irritable Bowel Disease and Alzheimer’s Disease Diagnostics (UCLA Case No. 2024-222)
UCLA researchers in the School of Dentistry and section of Biosystems and Function have developed a novel diagnostic protocol to accurately categorize both the virome and microbiome of the oral-gut-brain axis for periodontitis, irritable bowel disease, and Alzheimer’s disease pathologies. BACKGROUND: Humans are host to a large and diverse set...
Published: 1/7/2026   |   Updated: 1/7/2026   |   Inventor(s): Yvonne Kapila
Keywords(s):  
Category(s): Diagnostic Markers > Targets And Assays, Platforms > Diagnostic Platform Technologies
Generation of Therapeutic Human Anti-Trop-2 Extracellular Domain Antibodies (UCLA Case No. 2026-026)
UCLA researchers from the Department of Molecular and Medical Pharmacology and the Department of Microbiology, Immunology and Molecular Genetics have developed a panel of human antibodies and chimeric antigen receptors targeting Trop-2, providing diagnostic and therapeutic resources for targeting Trop2-driven cancer. BACKGROUND: Trophoblast cell surface...
Published: 12/23/2025   |   Updated: 12/23/2025   |   Inventor(s): Tanya Stoyanova, Owen Witte
Keywords(s):  
Category(s): Diagnostic Markers > Cancer, Diagnostic Markers > Targets And Assays, Life Science Research Tools > Antibodies, Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy
NPEPPS Enhancers for Treating Tau-Induced Neurodegeneration (UCLA Case No. 2018-161)
UCLA researchers from the Department of Neurology have developed first-in-class small-molecule activators of NPEPPS that effectively lower pathological tau, offering a novel disease-modifying strategy for Alzheimer’s and other neurodegenerative disorders. BACKGROUND: Neurodegenerative dementias such as Alzheimer’s Disease (AD) and progressive...
Published: 10/22/2025   |   Updated: 10/22/2025   |   Inventor(s): Daniel Geschwind, Robert Damoiseaux, Liting Deng, Michael Jung, Jennifer Murphy, Gaoyuan Ma
Keywords(s):  
Category(s): Therapeutics > CNS and Neurology, Diagnostic Markers > Targets And Assays
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