Search Results - techpub+algolia+%3e+therapeutics

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Engineering Asymmetrically Glycosylated IgG Antibodies
Application A method to produce asymmetrically glycosylated antibodies for the treatment and prevention of diseases including cancer, auto-immune disorders, and infectious diseases. Key Benefits This strategy has potential to produce a new class of therapeutic antibodies for treating and preventing a wide range of human diseases. Market Summary Monoclonal...
Published: 6/22/2026   |   Updated: 6/15/2026   |   Inventor(s): Tala Azzam, Eric J. Sundberg, Jonathan Du, Diego Sastre
Keywords(s): Antibodies, Platform
Category(s): TechPub Algolia > Therapeutics
MTHFD2-Targeting Peptide Decoy for Chemotherapy-Resistant Cancers
Application An engineered decoy peptide, DMp39, targeting DLAT-MTHFD2 interaction, as a sensitizer for chemotherapy resistant cancer treatment. Key Benefits Restores chemotherapy sensitivity in resistant tumors. Targets the DLAT-MTHFD2 pathway with high specificity and minimal off-target toxicity. Market Summary Chemotherapy resistance remains...
Published: 6/22/2026   |   Updated: 6/15/2026   |   Inventor(s): Sumin Kang, Jung Seok Hwang, Jaehyun Kim
Keywords(s): Oncology Treatments, Protein and Peptide Therapeutics, Therapeutics
Category(s): TechPub Algolia > Therapeutics
MPL Protein Targeting for Cancer Therapy and Transplant Preparation
Application Non-genotoxic hematopoietic stem cell transplantation conditioning regimen. Key Benefits Selective depletion of hematopoietic stem cells creates adequate niche space to allow donor engraftment without significant off target effect. Non-genotoxic conditioning regimen. CAR-T cells can have an anti-MPL positive leukemia effect before...
Published: 4/27/2026   |   Updated: 4/27/2026   |   Inventor(s): Shanmuganathan (Shan) Chandrakasan, H. (Harold) Trent Spencer, Christopher Doering, Lauren Fleischer, Gianna Branella, Jaquelyn Zoine, Harrison Brown
Keywords(s): Antibodies, Cell Therapy, Oncology Treatments
Category(s): TechPub Algolia > Therapeutics
Automated Deep Brain Stimulation Programming
Application A program to optimize parameters for deep brain stimulation. Key Benefits Can provide patient-specific deep brain stimulation parameters. May reduce the frequency of programming clinic visits May improve clinical outcomes by selecting optimal stimulation parameters. Market Summary Deep brain stimulation (DBS) is currently approved...
Published: 3/10/2026   |   Updated: 3/2/2026   |   Inventor(s): Svjetlana Miocinovic, Babak Mahmoudi
Keywords(s): Hospital and Surgical Assistance, Neurology and Pain Treatments
Category(s): TechPub Algolia > Software, TechPub Algolia > Therapeutics
Next Gen Immune-Optimized Gene Delivery
Application An advanced gene therapy approach that improves therapeutic efficiency by protecting transgene expressing cells from host immune responses, through modulation of a key immune checkpoint pathway. Key Benefits Enhanced efficiency across viral and non-viral gene delivery systems, including AAV, lentivirus, LNPs, and electroporation. Enables...
Published: 6/15/2026   |   Updated: 2/23/2026   |   Inventor(s): Matthew (Matt) Gardner, Michael Kuipa, Abubakarr Koroma, Isai Leguizamo
Keywords(s): Biologics, Cell Therapy, Gene Therapy and Editing, Immunology and Inflammation Treatments, Oncology Treatments, Platform, Regenerative Medicine
Category(s): TechPub Algolia > Therapeutics
Targeted Candidalysin Binders for Fungal Infection Control
Application A theranostic scaffold-derived protein that neutralizes candidalysin toxin. Key Benefits Different mechanism of action compared to current antifungal drugs, reducing the risk of resistance. Derived from human protein for lower immune response and produced cost-effectively in simple bacterial media. Small size improves tissue penetration...
Published: 4/27/2026   |   Updated: 1/20/2026   |   Inventor(s): Sohail Khoshnevis, Eric J. Sundberg, Maros Huliciak
Keywords(s): Diagnostics, Drug Discovery, Hydrogels, Protein and Peptide Therapeutics, Therapeutics
Category(s): TechPub Algolia > Therapeutics
Methioninase Inducing Virus for Anti-Cancer Therapy
Application A set of viral constructs that induce regulatable expression of methionine degrading enzyme for treatment of brain tumors. Key Benefits Built-in Tet-responsive element ensures precise regulation, preventing unwanted enzyme activity. IL-2 signal directs the enzyme for secretion, optimizing its therapeutic impact. Specific delivery...
Published: 6/15/2026   |   Updated: 12/9/2025   |   Inventor(s): Leon McSwain, Andrey Tikunov, Timothy R. Gershon
Keywords(s): Drug Discovery, Enzyme and Protein Research, Oncology Treatments, Therapeutics
Category(s): TechPub Algolia, TechPub Algolia > Therapeutics
Precision Protein Repair Platform for Missense Mutations
Application This technology enables targeted chemical correction of missense mutations in proteins using a modular heterotrifunctional molecule platform. Key Benefits Restores protein function by chemically mimicking healthy amino acid side chains. Modular toolkit allows rapid customization for diverse protein targets. Validated across multiple...
Published: 3/30/2026   |   Updated: 11/7/2025   |   Inventor(s): Monika Raj
Keywords(s): Drug Discovery, Drug Target Identification, Enzyme and Protein Research, Protein and Peptide Therapeutics, Research Tools
Category(s): TechPub Algolia > Therapeutics
Protein Polymers for Organelle Engineering
Application Protein polymers enabling engineering of human membraneless organelles. Key Benefits Versatile applications across immunotherapy, cell therapy, and other therapeutic modalities. High biocompatibility with minimal reactivity with endogenous molecules. Deployable for organelle-level functionalization of human cells. Market Summary Proteins...
Published: 5/22/2026   |   Updated: 11/7/2025   |   Inventor(s): Felipe Quiroz, Ian Sicher, Spencer Hayes, Maria Giraldo-Castaño, Mariell Pascual, Alexa Avecilla
Keywords(s): Biomaterials, Cell Therapy, Immunotherapy, Protein and Peptide Therapeutics, Regenerative Medicine, Research Tools
Category(s): TechPub Algolia > Therapeutics
Gene Editing for Head and Neck Cancer Treatment
Application Method for delivering gene-editing therapeutic in head and neck cancers. Key Benefits CRISPR/CAS9-based gene editing mechanism targeting novel disease-modifying gene. Liquid nanoparticle encapsulation permitting in vivo delivery. Market Summary Head and neck cancers (HNC) are the 7th most common global cancer, accounting for 3%...
Published: 5/22/2026   |   Updated: 11/7/2025   |   Inventor(s): Yong Teng, Yamin Li
Keywords(s): Drug Discovery, Drug Target Identification, Gene Therapy and Editing, Nanoparticle Drug Delivery, Oncology Treatments, Reagents, Biomaterials, and Plasmids
Category(s): TechPub Algolia > Therapeutics
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