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Increasing Efficiency of Anti-Tumor Immune Checkpoint Blockade Therapy by Manipulating Tumor-Associated Macrophages
A method to manipulate tumor-associated macrophages by targeting the mitochondrial electron transport chain, improving the efficacy of immune checkpoint blockade cancer therapies. Problem: Many cancer therapeutics work by activating the immune system to attack a tumor. These drugs, known as immune checkpoint blockade (ICB) therapies, commonly fail because...
Published: 5/13/2026   |   Updated: 5/13/2026   |   Inventor(s): Jorge Henao-Mejia, Megan Clark
Keywords(s): Drug Target, Immunology, Oncology
Category(s): Technology Classifications > Therapeutics