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Search Results - chiara+zurla
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Inhaled dry powders of nucleic acid-polymer polyplexes
Eliminates mRNA cold chain delivering inhalable powders with 71% aerosol efficiency. This technology creates stable, inhalable dry powders of mRNA-polymer complexes using thin-film freeze-drying, enabling room-temperature storage and efficient pulmonary delivery of RNA therapeutics, including CRISPR, for treating lung diseases without the need for...
Published: 5/11/2026
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Updated: 5/11/2026
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Inventor(s):
Zhengrong Cui
,
Bhupendra Giri
,
Philip Santangelo
,
Chiara Zurla
,
Donald Owens
,
Gregory Davenport
,
Chaeho Moon
Keywords(s):
Category(s):
Life sciences > Therapeutics > Drug delivery
,
Life sciences > Therapeutics > Formulation
Treatment for Dengue Virus (DENV) Infection
Application Antiviral therapeutic for multiple Dengue virus serotypes. Key Benefits Targets conserved regions of DENV genomes, enabling efficacy across serotypes. Mitigates lethal infections with a single lipid nanoparticle (LNP) based dose in mice. Minimal off-target effects. Market Summary Despite 390+ million annual DENV infections, there...
Published: 2/23/2026
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Updated: 10/30/2025
|
Inventor(s):
Philip Santangelo
,
Daryll Vanover
,
Chiara Zurla
,
Lorena Carvalho de Souza Chaves
Keywords(s):
DNA and RNA Vaccines
,
Drug Discovery
,
Drug Target Identification
,
Microbiology and Infectious Disease Treatments
Category(s):
TechPub Algolia > Therapeutics