Search Results - chaeho+moon

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Inhaled dry powders of nucleic acid-polymer polyplexes
Eliminates mRNA cold chain delivering inhalable powders with 71% aerosol efficiency. This technology creates stable, inhalable dry powders of mRNA-polymer complexes using thin-film freeze-drying, enabling room-temperature storage and efficient pulmonary delivery of RNA therapeutics, including CRISPR, for treating lung diseases without the need for...
Published: 5/11/2026   |   Updated: 5/11/2026   |   Inventor(s): Zhengrong Cui, Bhupendra Giri, Philip Santangelo, Chiara Zurla, Donald Owens, Gregory Davenport, Chaeho Moon
Keywords(s):  
Category(s): Life sciences > Therapeutics > Drug delivery, Life sciences > Therapeutics > Formulation
Thin film freezing technology for stable dry formulations of mRNA therapeutics
A thin film freezing method transforms mRNA and lipid nanoparticles into stable dry powders that retain their effectiveness and size. This eliminates the need for ultra-cold storage, allowing the powders to be inhaled or reconstituted, improving the distribution of mRNA therapies. Background mRNA therapeutics represent a groundbreaking advancement...
Published: 1/13/2026   |   Updated: 1/8/2026   |   Inventor(s): Robert Williams, Chaeho Moon, Sawittree Sahakijpijarn, Haiyue Xu, Zhengrong Cui
Keywords(s):  
Category(s): Life sciences > Therapeutics > Small molecule, Life sciences > Therapeutics > Drug delivery