Search Results - traumatic+brain+injury

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Device for Simulating Explosive Blast and Imaging Biological Specimens
Summary: Researchers at the National Institute of Child Health and Human Development (NICHD) developed a device simulating a blast shock wave of the type produced by explosive devices such as bombs. The invention allows for the real-time study of blast effects on in vitro cell models. NICHD researchers seek licensing opportunities to further develop...
Published: 4/30/2026   |   Updated: 8/2/2023   |   Inventor(s): Rea Ravin, Paul Blank, Alex Steinkamp, Joshua Zimmerberg, Sergey Bezrukov, Kim Lee Mcafee
Keywords(s): Central Nervous System, CNS, explosive blast, National Institute of Child Health and Human Development, NICHD, SIMULATOR, TBI, Traumatic Brain Injury, Zimmerberg
Category(s): Application > Non-Medical Devices, Collaboration Sought > Collaboration, Application > Medical Devices, TherapeuticArea > Neurology, Collaboration Sought > Licensing
Tamperless Tensor Elastography Imaging
Summary: The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) seeks research co-development partners and/or licensees for the development of tamper-less tensor elastography imaging in assessing disease (e.g., cancer), normal and abnormal developmental processes, degeneration and trauma in the brain and other soft...
Published: 4/23/2026   |   Updated: 8/2/2023   |   Inventor(s): Peter Basser, Magdoom Mohamed Kulam Najmudeen
Keywords(s): Alzheimer’s Disease, Anisotropy, Basse, brain, CANCER, Elasticity Tensor, Elastography, Eunice Kennedy Shriver National Institute of Child Health an, Magnetic Resonance Imaging, MRI, Najmudeen, NICHD, TBI, TRAUMA, Traumatic Brain Injury
Category(s): TherapeuticArea > Neurology, Application > Diagnostics, TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing
MRI-Based Method for Characterizing Axonal Microstructure in Traumatic Brain Injury
Abstract: Neurites of the central nervous system can be conceptualized as cylindrical pores with finite lengths and radii. In response to physical trauma, axons may assume a “beaded” morphology which alters their ability to conduct electrical impulses, impairing brain function. These microstructural changes are thought to underlie some of the cognitive...
Published: 4/22/2025   |   Updated: 8/2/2023   |   Inventor(s): Peter Basser, Dan Benjamini, Michal Komlosh
Keywords(s): Magnetic Resonance Imaging, MRI, MRI diagnostic, Neurites, Peripheral Nervous System, PNS, TBI, Traumatic Brain Injury
Category(s): Application > Diagnostics, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Neurology
Multidimensional MRI Signature for Specific Detection of Traumatic Brain Injury In Vivo
Summary: The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) seeks research co-development partners and/or licensees for the development of multidimensional MRI-based methods. Description of Technology: Traumatic brain injury (TBI) represents a major medical, social and economic concern worldwide due to significant...
Published: 4/23/2026   |   Updated: 8/2/2023   |   Inventor(s): Dan Benjamini, Peter Basser, Diego Iacono
Keywords(s): Amyloid Precursor Protein, Be, DAI, Diffuse Axonal Injury, Eunice Kennedy Shriver National Institute of Child Health an, Magnetic Resonance Imaging, MRI, MULTIDIMENSIONAL, NICHD, TAI, TBI, Traumatic Axonal Injury, Traumatic Brain Injury
Category(s): TherapeuticArea > Neurology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Diagnostics
Reagents Targeting Neurodegenerative Diseases and Traumatic Brain Injury
Misfolding and aggregation of proteins, such as beta-amyloid (Aß), alpha-synuclein (a-syn), tau and TAR DNA-binding protein 43 (TDP-43), have been strongly correlated with early onset of neurodegenerative diseases such as Alzheimer's Disease (AD), Parkinson's Disease (PD), Frontotemporal Dementia (FTD), amyotrophic lateral sclerosis (ALS) and...
Published: 2/26/2026   |   Updated: 4/19/2023   |   Inventor(s): Michael Sierks, Stephanie Williams
Keywords(s): Antibodies, Antigen-specific Therapies, Bioassay, biomarker, ELISA, Mental Disorders, Traumatic Brain Injury
Category(s): Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Neurodegenerative Disease Technologies, Non-Cancer Therapeutics, Proteomic Assays/Reagents/Tools
Passive Wireless Multi-Channel Stimulator
Passive, wireless stimulators have received significant interest due to their ability to provide therapy and rehabilitation by targeting an organ with monophasic or biphasic stimulation pulses. Wireless stimulators are advantageous because they reduce the risk of infection and inflammation by eliminating wires that protrude through the skin. Extending...
Published: 2/26/2026   |   Updated: 4/7/2023   |   Inventor(s): Jennifer Blain Christen, Shiyi Liu, Ahmed Abed Benbuk, Daniel Gulick
Keywords(s): Brain and Machine Interface, Brain stimulation, Cancer, CNS Therapeutics, Epilepsy, Flexible electronics, Medical Device, Neural implants, Neural Prostheses, Neurostim and Neuromodulation, Neurostimulation, Stimulator, Traumatic Brain Injury
Category(s): Life Science (All LS Techs), Medical Devices
2022-243 A Computerized Tool Designed to Provide Cognitive Assistance for the Diagnosis of the Neurological Symptoms that may Appear After a Head Trauma in Children and Young Adults
Summary: UCLA researchers in the David Geffen School of Medicine and USC researchers in the Viterbi School of Engineering have developed a computerized diagnostic tool which can identify and rank the probability of neurological symptoms that may appear after a head trauma in childhood and adolescence solely based on patient-reported symptoms. Background: Head...
Published: 2/14/2025   |   Updated: 7/13/2022   |   Inventor(s): Shahram Yazdani, Ronald Henry, Christopher Giza
Keywords(s): Algorithm, Artificial Intelligence, Artificial Neural Network, Diagnostic Test, Head Injury, Medical Device, Software & Algorithms, Spinal Cord Injury, Trauma (Medicine), Traumatic Brain Injury
Category(s): Software & Algorithms, Software & Algorithms > Artificial Intelligence & Machine Learning, Medical Devices