Search Results - thyroid

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Humanized Mouse Model to Study Mesothelin (MSLN) -targeted Cancer Therapeutics: Bl6/TPO Mice
Summary: The NCI Laboratory of Molecular Biology is seeking parties interested in licensing a genetically engineered mouse model expressing hMSLN in the thyroid gland for commercialization in the field of cancer therapeutics and research targeting mesothelin-expressing tumors. Description of Technology: Mesothelin (MSLN) is an antigen highly expressed...
Published: 4/24/2026   |   Updated: 8/2/2023   |   Inventor(s): Christine Alewine, Serguei Kozlov, Xianyu Zhang, Theresa Guerin, Theresa O'Sullivan, Norman Collins, Jerome Schlomer
Keywords(s): Alewine, Bl6/TPO, Cancer Animal Model, hMSLN, Humanized Mice, MESOTHELIN, MSLN, Murine Model, THYROID
Category(s): Collaboration Sought > Licensing, Application > Research Materials, TherapeuticArea > Oncology
Stratifying the risk of malignancy in indeterminate thyroid nodules
Project ID D2019-45 Thyroid cancer is the most common endocrine cancer globally, and accounts for 3.4% of all new cancer cases in the US. Although several clinical guidelines to detect/manage thyroid nodules are available, a great deal of controversy still exists around the optimal approach for diagnosis. Approximately 20-30% of cytology results from...
Published: 4/6/2026   |   Updated: 1/11/2021   |   Inventor(s): Shahnawaz Imam, Juan Jaume
Keywords(s): Atypia of undetermined significance (AUS), Euthyroid Hashimoto thyroiditis (EHT), Fine needle aspiration (FNA), Follicular lesion of undetermined significance (FLUS), Thyroid, Thyroid cancer diagnostic/prognostic markers
Category(s): Diagnostics, Oncology