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Search Results - r
17591
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Title
ID
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Multip
r
onged Composite Protocol for High-Efficiency Deep Tissue RNA Delivery and Expression
An
R
NA transfection and protein expression approach comprising lipid nanoparticles, hyaluronic acid, and photostimulation Problem: As the field of cell modification has expanded, researchers have sought more effective methods for nucleic acid (NA) delivery into cells. RNA transfection is easier to facilitate and control than DNA transfection, making...
Published: 5/13/2026
|
Updated: 5/13/2026
|
Inventor(s):
James Ebe
r
wine
,
Jai-Yoon Sul
,
Hyunbum Kim
Keywords(s):
Cell The
r
apy
,
Gene Editing
,
Gene The
r
apy
,
Platfo
r
m Technology
,
P
r
otein/Peptide (Non-Antibody)
Category(s):
Technology Classifications > Medical Devices
,
Technology Classifications >
R
esearch Tools & Reagents
,
Technology Classifications > The
r
apeutics
No
r
thwestern Startup: Akava Therapeutics
Founded: 2019 No
r
thwestern Inventor: Richard Silverman Weinberg College of Arts and Sciences Department of Chemistry and Department of Molecular Biosciences Feinberg School of Medicine Department of Pharmacology AKAVA Therapeutics is developing first-in-class small molecule therapeutics that inhibit enzymes, inhibit cancer, and inhibit protein...
Published: 5/13/2026
|
Updated: 5/13/2026
|
Inventor(s):
Keywords(s):
ALS - Amyot
r
ophic Lateral Sclerosis
,
Neu
r
odegenerative disease
,
Neu
r
ology
,
The
r
apeutics
Category(s):
Medical
Tibial Tube
r
cle Osteotomy Fixation Device
Fixation device to secu
r
e bone fragment of tibial tuberosity to native bone after osteotomy surgical procedure. Background: Standard osteotomy techniques to join the tibial tubercle fragment to native bone include screw fixation alone or fixation with wire or suture, which are not reliable methods to holding the bone in place to avoid displacement...
Published: 5/13/2026
|
Updated: 5/13/2026
|
Inventor(s):
Timothy Dam
r
on
Keywords(s):
biomedical
,
biomedical enginee
r
ing
,
ha
r
dware
,
healthca
r
e
,
inst
r
umentation
,
medical devices
,
medical equipment
,
o
r
thopedics
,
osteoa
r
thritis
,
su
r
gery
,
sutu
r
ing technique
,
Technologies
Category(s):
Technology Classifications > Medical Devices
,
Campus > Upstate Medical Unive
r
sity
Inc
r
easing Efficiency of Anti-Tumor Immune Checkpoint Blockade Therapy by Manipulating Tumor-Associated Macrophages
A method to manipulate tumo
r
-associated macrophages by targeting the mitochondrial electron transport chain, improving the efficacy of immune checkpoint blockade cancer therapies. Problem: Many cancer therapeutics work by activating the immune system to attack a tumor. These drugs, known as immune checkpoint blockade (ICB) therapies, commonly fail because...
Published: 5/13/2026
|
Updated: 5/13/2026
|
Inventor(s):
Jo
r
ge Henao-Mejia
,
Megan Cla
r
k
Keywords(s):
D
r
ug Target
,
Immunology
,
Oncology
Category(s):
Technology Classifications > The
r
apeutics
Coatings containing pola
r
additives and their use as ice shedding surfaces.
This invention
r
elates to advanced polyurea-siloxane (PU) coatings modified with natural deep eutectic solvents (NADES) and co-curing additives to improve ice-shedding performance under real-world conditions. The coating system incorporates choline chloride-glycerol NADES into a moisture-curable polymer matrix, enabling the formation of microphase-separated...
Published: 5/13/2026
|
Updated: 5/13/2026
|
Inventor(s):
Dean Webste
r
,
Geetisubh
r
a Jena
,
Olena Shaf
r
anska
,
Emma Nissen
Keywords(s):
Anti-icing; Ice Shedding
Category(s):
Technologies
,
Technologies > Chemist
r
y & Materials
,
Technologies > Paints & Coatings
'ND
R
edvelvet' small red bean (NDF151006-2)
‘ND
R
edvelvet’ small red bean was released in 2026 by the North Dakota Agricultural Experiment Station. Developed from the cross SR9-4/'Rio Rojo', ND Redvelvet has demonstrated competitive agronomic performance compared to other small red varieties commonly grown in the region. It matures in approximately 101 days and offers improved...
Published: 5/13/2026
|
Updated: 5/13/2026
|
Inventor(s):
Juan Oso
r
no
Keywords(s):
Ag
r
iculture
,
Plants
Category(s):
Technologies > Ag
r
icultural Varieties
,
Technologies > Ag
r
icultural Varieties > Dry Beans
Multifunctional Fluo
r
opolymer Composite Films and Methods of Preparing the Same
This technology involves the development of multifunctional PVDF-based composite films inco
r
porating two commercial alumina nanoparticle grades—SpectrAl® 81 and SpectrAl® 51—and recycled micronized ground tire rubber (GTR). The films are fabricated using a scalable solution-casting process in which PVDF and selected filler compositions...
Published: 5/13/2026
|
Updated: 5/13/2026
|
Inventor(s):
Ma
r
cel Roy Domalanta
,
Eugene Caldona
Keywords(s):
Composites
,
Paints & Coatings
Category(s):
Technologies
,
Technologies > Chemist
r
y & Materials
,
Technologies > Paints & Coatings
'ND Pink-Slippe
r
' light red kidney bean (ND151660)
R
eleased in 2026 by the North Dakota Agricultural Experiment Station, ‘ND Pink-Slipper’ light red kidney (LRK) bean combines strong agronomic performance with excellent seed quality. Originating from the cross 'Clouseau'/'Rosie', it has performed competitively with other LRK varieties commonly grown in the region while maturing...
Published: 5/13/2026
|
Updated: 5/13/2026
|
Inventor(s):
Juan Oso
r
no
Keywords(s):
Ag
r
iculture
,
Plants
Category(s):
Technologies > Ag
r
icultural Varieties
,
Technologies > Ag
r
icultural Varieties > Dry Beans
Epigenetic Gene Editing in Ca
r
diomyopathy to Improve Heart Function
SHO
R
T DESCRIPTION A precision cardiac gene‑regulation platform that deletes a MYH7 enhancer to shift ventricular myosin isoform balance toward faster α‑MHC and activates upstream MYH6 enhancers to increase MYH6 expression and improve contractility, creating a dual toolkit for disease‑modifying therapy in cardiomyopathy and heart failure. INVENTORS Elizabeth...
Published: 5/13/2026
|
Updated: 5/12/2026
|
Inventor(s):
Keywords(s):
Ca
r
diology and Cardiovascular disease
,
Ca
r
diomyopathy
,
Gene the
r
apy
,
R
egenerative medicine
,
The
r
apeutics
Category(s):
Life Sciences > The
r
apeutics
Delive
r
y of exogenous protein/peptide cargoes to the cell cytosol
Su
r
vival curves of weanling mice immunized with LFn-LACV-Gc or LFn-LACV-N compared with LFn-ZIKV-NS3 and subsequently challenged with LACV Invention Summary: Novel T cell-based vaccine was developed by utilizing a fusion protein by binding a target protein or peptide molecule with transport factor derived from Bacteria. The target protein...
Published: 5/12/2026
|
Updated: 5/12/2026
|
Inventor(s):
Bobby B
r
ooke Herrera
Keywords(s):
Category(s):
Technology Classifications > Healthca
r
e & Life Sciences
,
Technology Classifications > Infectious Disease
,
Technology Classifications > Vaccine
1
2
3
4
5
6
7
8
9
10
...