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Search Results - isabella+hetherington
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mRNA Nanotherapy for Atherosclerotic Cardiovascular Disease
Advantages: Cell‑Selective Mechanism: miR‑126 switch enables p27 expression only in VSMCs, preserving endothelial healing Dual‑Action Therapeutic: A single mRNA combines anti‑proliferative p27 expression with siRNA‑mediated IL‑1β knockdown, targeting two major drivers of plaque progression. Demonstrated In‑Vivo Efficacy: Proven reduction...
Published: 5/11/2026
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Updated: 7/19/2023
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Inventor(s):
Isabella Hetherington
Keywords(s):
Cardiovascular Diseases
,
Drug Delivery and Nanomedicine
Category(s):
Technology Classifications > Medical > Biotechnology
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Technology Classifications > Medical > Therapeutics
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Technology Classifications > Medical > Pharmaceuticals