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Northw
e
stern Startup: Akava Therapeutics
Found
e
d: 2019 Northwestern Inventor: Richard Silverman Weinberg College of Arts and Sciences Department of Chemistry and Department of Molecular Biosciences Feinberg School of Medicine Department of Pharmacology AKAVA Therapeutics is developing first-in-class small molecule therapeutics that inhibit enzymes, inhibit cancer, and inhibit protein...
Published: 5/13/2026
|
Updated: 5/13/2026
|
Inventor(s):
Keywords(s):
Category(s):
M
e
dical
Tibial Tub
e
rcle Osteotomy Fixation Device
Fixation d
e
vice to secure bone fragment of tibial tuberosity to native bone after osteotomy surgical procedure. Background: Standard osteotomy techniques to join the tibial tubercle fragment to native bone include screw fixation alone or fixation with wire or suture, which are not reliable methods to holding the bone in place to avoid displacement...
Published: 5/13/2026
|
Updated: 5/13/2026
|
Inventor(s):
Timothy Damron
Keywords(s):
biom
e
dical
,
biom
e
dical engineering
,
hardwar
e
,
h
e
althcare
,
instrum
e
ntation
,
m
e
dical devices
,
m
e
dical equipment
,
orthop
e
dics
,
ost
e
oarthritis
,
surg
e
ry
,
suturing t
e
chnique
,
T
e
chnologies
Category(s):
T
e
chnology Classifications > Medical Devices
,
Campus > Upstat
e
Medical University
Incr
e
asing Efficiency of Anti-Tumor Immune Checkpoint Blockade Therapy by Manipulating Tumor-Associated Macrophages
A m
e
thod to manipulate tumor-associated macrophages by targeting the mitochondrial electron transport chain, improving the efficacy of immune checkpoint blockade cancer therapies. Problem: Many cancer therapeutics work by activating the immune system to attack a tumor. These drugs, known as immune checkpoint blockade (ICB) therapies, commonly fail because...
Published: 5/13/2026
|
Updated: 5/13/2026
|
Inventor(s):
Jorg
e
Henao-Mejia
,
M
e
gan Clark
Keywords(s):
Drug Targ
e
t
,
Immunology
,
Oncology
Category(s):
T
e
chnology Classifications > Therapeutics
Coatings containing polar additiv
e
s and their use as ice shedding surfaces.
This inv
e
ntion relates to advanced polyurea-siloxane (PU) coatings modified with natural deep eutectic solvents (NADES) and co-curing additives to improve ice-shedding performance under real-world conditions. The coating system incorporates choline chloride-glycerol NADES into a moisture-curable polymer matrix, enabling the formation of microphase-separated...
Published: 5/13/2026
|
Updated: 5/13/2026
|
Inventor(s):
D
e
an Webster
,
G
e
etisubhra Jena
,
Ol
e
na Shafranska
,
E
mma Nissen
Keywords(s):
Anti-icing; Ic
e
Shedding
Category(s):
T
e
chnologies
,
T
e
chnologies > Chemistry & Materials
,
T
e
chnologies > Paints & Coatings
'ND R
e
dvelvet' small red bean (NDF151006-2)
‘ND R
e
dvelvet’ small red bean was released in 2026 by the North Dakota Agricultural Experiment Station. Developed from the cross SR9-4/'Rio Rojo', ND Redvelvet has demonstrated competitive agronomic performance compared to other small red varieties commonly grown in the region. It matures in approximately 101 days and offers improved...
Published: 5/13/2026
|
Updated: 5/13/2026
|
Inventor(s):
Juan Osorno
Keywords(s):
Agricultur
e
,
Plants
Category(s):
T
e
chnologies > Agricultural Varieties
,
T
e
chnologies > Agricultural Varieties > Dry Beans
Multifunctional Fluoropolym
e
r Composite Films and Methods of Preparing the Same
This t
e
chnology involves the development of multifunctional PVDF-based composite films incorporating two commercial alumina nanoparticle grades—SpectrAl® 81 and SpectrAl® 51—and recycled micronized ground tire rubber (GTR). The films are fabricated using a scalable solution-casting process in which PVDF and selected filler compositions...
Published: 5/13/2026
|
Updated: 5/13/2026
|
Inventor(s):
Marc
e
l Roy Domalanta
,
E
ugene Caldona
Keywords(s):
Composit
e
s
,
Paints & Coatings
Category(s):
T
e
chnologies
,
T
e
chnologies > Chemistry & Materials
,
T
e
chnologies > Paints & Coatings
'ND Pink-Slipp
e
r' light red kidney bean (ND151660)
R
e
leased in 2026 by the North Dakota Agricultural Experiment Station, ‘ND Pink-Slipper’ light red kidney (LRK) bean combines strong agronomic performance with excellent seed quality. Originating from the cross 'Clouseau'/'Rosie', it has performed competitively with other LRK varieties commonly grown in the region while maturing...
Published: 5/13/2026
|
Updated: 5/13/2026
|
Inventor(s):
Juan Osorno
Keywords(s):
Agricultur
e
,
Plants
Category(s):
T
e
chnologies > Agricultural Varieties
,
T
e
chnologies > Agricultural Varieties > Dry Beans
E
pigenetic Gene Editing in Cardiomyopathy to Improve Heart Function
SHORT D
E
SCRIPTION A precision cardiac gene‑regulation platform that deletes a MYH7 enhancer to shift ventricular myosin isoform balance toward faster α‑MHC and activates upstream MYH6 enhancers to increase MYH6 expression and improve contractility, creating a dual toolkit for disease‑modifying therapy in cardiomyopathy and heart failure. INVENTORS Elizabeth...
Published: 5/12/2026
|
Updated: 5/12/2026
|
Inventor(s):
Keywords(s):
Cardiology and Cardiovascular dis
e
ase
,
Cardiomyopathy
,
G
e
ne therapy
,
R
e
generative medicine
,
Th
e
rapeutics
Category(s):
Lif
e
Sciences > Therapeutics
D
e
livery of exogenous protein/peptide cargoes to the cell cytosol
Survival curv
e
s of weanling mice immunized with LFn-LACV-Gc or LFn-LACV-N compared with LFn-ZIKV-NS3 and subsequently challenged with LACV Invention Summary: Novel T cell-based vaccine was developed by utilizing a fusion protein by binding a target protein or peptide molecule with transport factor derived from Bacteria. The target protein...
Published: 5/12/2026
|
Updated: 5/12/2026
|
Inventor(s):
Bobby Brook
e
Herrera
Keywords(s):
Category(s):
T
e
chnology Classifications > Healthcare & Life Sciences
,
T
e
chnology Classifications > Infectious Disease
,
T
e
chnology Classifications > Vaccine
Non-Invasiv
e
ly Transferring Spatiotemporal Neural Population and Network Activation Patterns
E
liminates post-surgical functional loss by relocating critical neural networks via BCI neuromodulation. This technology non-invasively shifts brain functions from damaged to healthy areas using targeted brain stimulation and brain-computer interface training, harnessing neuroplasticity to preserve or restore abilities in patients, such as those undergoing...
Published: 5/12/2026
|
Updated: 5/12/2026
|
Inventor(s):
Jos
e
del R Millan
,
Akhil Surapan
e
ni
Keywords(s):
Category(s):
Lif
e
sciences > Medical technology > TechBio (software innovation in healthcare)
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