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Fast, Background-free Detection of Nucleic Acid Sequences Using DNA Nanoswitches
This technology introduces DNA-based "nanoswitches"—innovative nanostructures that enable precise and efficient detection of target analytes through conformational changes. Background: Accurate detection of specific molecules, such as DNA sequences or other analytes, is fundamental in medical diagnostics, environmental monitoring,...
Published: 5/6/2026   |   Updated: 5/5/2026   |   Inventor(s): Kenneth Halvorsen, Wesley Wong, Arun Richard Chandrasekaran
Keywords(s):  
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering
ATR_FTIR spectroscopy of saliva and machine learning as a screening test for the Sjögren disease
This technology uses saliva analysis with infrared spectroscopy and machine learning to provide a fast, non-invasive, and accurate test for Sjögren’s Disease, filtering out unreliable data to improve diagnosis and potentially screen for other diseases. Background: Sjögren’s disease is a chronic autoimmune disorder that primarily...
Published: 5/5/2026   |   Updated: 5/4/2026   |   Inventor(s): Igor Lednev, Bhavikkumar Vyas, Jürgen Popp, Oleg Ryabchykov
Keywords(s): diagnostics, Salivary biomarkers, Sjogren Disease, spectroscopy, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics
Temporal Control of CRISPR-Cas9 using Bio-orthogonal Chemistry.
This technology enables precise, time-controlled activation or deactivation of CRISPR-Cas9 genome editing using biocompatible chemical reactions, reducing off-target effects and improving the safety and accuracy of gene editing for research and therapeutic applications. Background: Genome editing technologies, particularly CRISPR-Cas9, have revolutionized...
Published: 5/5/2026   |   Updated: 5/4/2026   |   Inventor(s): Maksim Royzen, Bhoomika Pandit
Keywords(s): biochemistry, CRISPR, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Gene Therapy
Bruton's Tyrosine Kinase as Anti-Cancer Drug Target
This technology identifies Bruton's Tyrosine Kinase (BTK) as a novel target in breast cancer therapy and provides methods for treatment and diagnosis by inhibiting a specific BTK variant. Background: Protein tyrosine kinases (PTKs) are essential enzymes involved in cellular communication and regulation, often playing a significant role in cancer...
Published: 5/5/2026   |   Updated: 5/4/2026   |   Inventor(s): Douglas Conklin, Antonis Kourtidis, Cheryl Eifert
Keywords(s): breast cancer, cancer, TAF, Technologies, therapeutic targets
Category(s): Technology Classifications > Therapeutics and Vaccines, Technology Classifications > Biomedical Science and Engineering, Campus > University at Albany
Spectroscopic Method for Diagnostics of Alzheimer's Disease
This technology provides a non-invasive, spectroscopic method using Raman spectroscopy to diagnose and monitor Alzheimer’s disease by analyzing biochemical changes in blood serum. Background: Alzheimer’s disease presents significant diagnostic challenges, often requiring invasive or costly procedures with limited early detection capabilities....
Published: 5/6/2026   |   Updated: 5/4/2026   |   Inventor(s): Igor Lednev
Keywords(s): Alzheimer's, blood, diagnostics, neurodegeneration, Raman spectroscopy, statistical analysis, TAF, Technologies, vibrational spectroscopy
Category(s): Technology Classifications > Diagnostics, Campus > University at Albany
Diagnosing Alzheimer's via Raman Spectroscopic Analysis of Saliva
This technology provides a non-invasive method for early detection of cognitive diseases using spectroscopic analysis of saliva samples combined with advanced statistical and neural network models. Background: Cognitive diseases such as Alzheimer's and mild cognitive impairment (MCI) represent significant challenges in healthcare due to their...
Published: 5/5/2026   |   Updated: 5/4/2026   |   Inventor(s): Igor Lednev, Nicole Ralbovsky, Cay Anderson-Hanley
Keywords(s): Alzheimer's, diagnostics, saliva, solar cells, TAF, Technologies
Category(s): Technology Classifications > Diagnostics, Campus > University at Albany
A layer-by-layer mass spectrometry intensity method for de novo direct sequencing of RNA therapeutics and impurities
3D NGMS-Seq is a mass spectrometry-based technology that accurately sequences all RNA types and impurities in mixed samples, enabling comprehensive analysis of RNA therapeutics for drug development, quality control, and regulatory compliance. Background: The field of RNA-based therapeutics has experienced rapid growth due to the success of mRNA vaccines...
Published: 5/7/2026   |   Updated: 5/4/2026   |   Inventor(s): Shenglong Zhang
Keywords(s): Mass spectrometry imaging, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Bioinformatics, Technology Classifications > Therapeutics and Vaccines
Improving the sensitivity and range of detection with ligation of DNA nanoswitches
This technology uses enzymatic ligation in DNA nanoswitches to detect very short or rare DNA and RNA sequences with high sensitivity, amplifying signals by recycling targets so even single molecules can be identified for diagnostics and research. Background: Nucleic acid detection is a cornerstone of modern molecular biology, diagnostics, and biotechnology,...
Published: 3/26/2026   |   Updated: 3/11/2026   |   Inventor(s): Kenneth Halvorsen, Jibin Punnoose, Vinod Morya
Keywords(s): DNA nanoswitches, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Biomedical Science and Engineering
A 3D printable mini-gel electrophoresis system and methods for use
This technology is a low-cost, 3D printable mini-gel electrophoresis system with built-in electrodes, enabling rapid, portable DNA analysis using battery power—ideal for education, fieldwork, and labs with limited resources. Background: Gel electrophoresis is a cornerstone technique in molecular biology, widely used for the separation and analysis...
Published: 3/26/2026   |   Updated: 3/9/2026   |   Inventor(s): Kenneth Halvorsen, Andrew Hayden, Vinod Morya
Keywords(s): 3D printing, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics
Expanding DNA nanoswitch utility with detection by aptamers
This technology integrates aptamers into DNA nanoswitches, enabling sensitive detection of a wide range of biomolecules—including proteins and small molecules—for use in diagnostics, research, and biosensing applications. Background: Molecular detection technologies are foundational in fields such as diagnostics, biomedical research,...
Published: 3/26/2026   |   Updated: 3/9/2026   |   Inventor(s): Kenneth Halvorsen, Arun Richard Chandrasekaran
Keywords(s): aptamers, DNA nanoswitches, Technologies
Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Biomedical Science and Engineering
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