Search Results - arvydas+maminishkis

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Biodegradable Tissue Scaffold for Multi-Tissue Transplantation
The National Eye Institute (NEI) seeks research co-development partners and/or licensees for the development of a biodegradable tissue scaffold designed for multi-tissue transplantation. This technology includes a dual-layer biodegradable tissue scaffold designed for the transplantation of multiple tissue types, such as retinal pigment epithelium (RPE)...
Published: 6/18/2026   |   Updated: 6/16/2026   |   Inventor(s): Arvydas Maminishkis, Kapil Bharti, Davide Ortolan, Ruchi Sharma
Keywords(s):  
Category(s): Application > Medical Devices, Application > Research Materials, Application > Therapeutics, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Ophthalmology
Snapwell Shipping Container for Live Cell Cultures
The National Eye Institute (NEI) seeks research co-development partners and/or licensees for the development of a novel shipping container designed to protect live cell cultures during transport. This technology includes a specialized container designed for the secure shipping of fragile cell cultures grown on the Snapwell insert system, preventing...
Published: 6/18/2026   |   Updated: 6/16/2026   |   Inventor(s): Arvydas Maminishkis
Keywords(s):  
Category(s): Application > Medical Devices, Application > Research Materials, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, ResearchProducts > Research Equipment, TherapeuticArea > Ophthalmology
Interferon Gamma for Retinal Fluid Absorption Restoration
The National Eye Institute (NEI) seeks research co-development partners and/or licensees for the development of Interferon gamma as a therapeutic agent to restore retinal fluid absorption. This technology includes the use of Interferon gamma to restore fluid absorption in retinal pigment epithelial (RPE) cells, specifically targeting the adverse effects...
Published: 6/18/2026   |   Updated: 6/16/2026   |   Inventor(s): Charlotte Reme, Sheldon Miller, Arvydas Maminishkis
Keywords(s):  
Category(s): Application > Therapeutics, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, TherapeuticArea > Ophthalmology
Interferon Gamma as a Therapeutic Agent for Proliferative Eye Diseases
The National Eye Institute (NEI) seeks research co-development partners and/or licensees for the development of Interferon-gamma as a therapeutic agent for proliferative eye diseases. This technology includes the use of Interferon-gamma (IFN-y) as a therapeutic agent to inhibit the proliferation and migration of human retinal pigment epithelial (RPE)...
Published: 6/18/2026   |   Updated: 6/16/2026   |   Inventor(s): Rong Li, Sheldon Miller, Arvydas Maminishkis
Keywords(s):  
Category(s): Application > Therapeutics, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Ophthalmology
Personalized Medicine Using Additive Manufacturing
THE CHALLENGE A major problem posed by the pharmaceutical industry is giving effective dosages while not giving excessive amounts of a particular drug. An estimated 80% of side effects in humans and animals are a direct result of inaccurate dosing because varying weights in patients. Additive manufacturing has emerged as a very promising method to...
Published: 6/26/2025   |   Updated: 10/2/2023   |   Inventor(s): Emily Wilts, Timothy Long, Christopher Williams, Da Ma
Keywords(s):  
Category(s): Technology Classifications > Additive Manufacturing, Technology Classifications > Biomedical, Technology Classifications > Chemicals/Materials, Technology Classifications > Pharmacology and Therapeutics
Tissue Clamp for Repeated Opening and Closure of Incisions/Wounds
Abstract: Medical clamps currently available are not efficient nor are they sufficiently precise in closure and alignment of the edges of an incision or wound. Many available designs are difficult to use and handle, especially in situations where repeated opening and closure of an incision or wound is required. The functional short-comings of existing...
Published: 4/22/2025   |   Updated: 8/2/2023   |   Inventor(s): Vladimir Khristov, Steven Charles, Juan Amaral, Arvydas Maminishkis, Kapil Bharti
Keywords(s): CLAMP, ocular surgery, sclera incision closure
Category(s): Collaboration Sought > Collaboration, Application > Non-Medical Devices, Application > Medical Devices, Collaboration Sought > Licensing, TherapeuticArea > Ear, Nose, & Throat, TherapeuticArea > Ophthalmology
Surgical Tool for Sub-retinal Tissue Implantation
Abstract: The accurate placement of transplanted tissue at a precise position in the retina is difficult but critical for a successful implementation of an ocular surgical intervention. Researchers at the National Eye Institute (NEI) developed a surgical tool (see image below) designed to place tissue patches, such as sheets of tissue, onto the retina...
Published: 4/22/2025   |   Updated: 8/2/2023   |   Inventor(s): Arvydas Maminishkis
Keywords(s): EYE, Intra-Ocular, Maminishkis, National Eye Institute, NEI, sub-retinal, surgical tool, tissue placement retina
Category(s): Collaboration Sought > Licensing, Application > Non-Medical Devices, Application > Medical Devices, TherapeuticArea > Ear, Nose, & Throat, TherapeuticArea > Ophthalmology
Devices for Improved Tissue Cryopreservation and Recovery
Abstract: Problem: Cryopreservation is a process where living biological materials like cells, tissues, and cell therapies (which are susceptible to damage caused by unregulated chemical kinetics) are preserved by cooling to very low temperatures in the presence of specific cryopreservation media that protects the biological material from damage. In...
Published: 4/22/2025   |   Updated: 8/2/2023   |   Inventor(s): Vladimir Khristov, Arvydas Maminishkis, Kapil Bharti
Keywords(s): Cell recovery, Cell thawing, Cell therapy, Cryopreservation, Defrost, National Eye Institute, NEI, Tissue transplant
Category(s): Collaboration Sought > Materials Available, Application > Medical Devices, TherapeuticArea > Immunology, TherapeuticArea > Dermatology, Collaboration Sought > Licensing, Application > Non-Medical Devices, TherapeuticArea > Oncology, Collaboration Sought > Collaboration, TherapeuticArea > Ear, Nose, & Throat, TherapeuticArea > Ophthalmology
Whole Tissue Protein Mapping
A tool and method for precise, high-throughput spatial mapping of proteins across whole tissue samples. Background: Spatial proteomics enables delineation of spatial localization of proteins within cells and tissues. This ability to identify and study the relative location and quantification of one or more proteins, whether ones that are endogenously...
Published: 6/19/2026   |   Updated: 7/24/2023   |   Inventor(s): Jun Qu, Ming Zhang, Min Ma
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Bioinformatics
Novel Methods for Generating Retinal Pigment Epithelium Cells from Induced Pluripotent Stem Cells
Abstract: The retinal pigment epithelial cells (RPE) make up a polarized monolayer in the vertebrate eye that separates the neural retina from the choroid, and performs a crucial role in retinal physiology by forming a blood-retinal barrier and closely interacting with photoreceptors to maintain visual function.  Many ophthalmic diseases, such as age-related...
Published: 4/22/2025   |   Updated: 7/14/2023   |   Inventor(s): Kapil Bharti, Kapil Bharti, Janine Davis, Sheldon Miller, Arvydas Maminishkis, Marc Ferrer-Alegre
Keywords(s): Age-related Macular Degeneration, AMD, DIFFERENTIATION, retinal pigment epithelial cells, STEM CELLS
Category(s): Collaboration Sought > Licensing, Application > Research Materials, Collaboration Sought > Collaboration, TherapeuticArea > Ear, Nose, & Throat, TherapeuticArea > Ophthalmology