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AIBP-Driven Lipid Raft Modification: A Novel Approach for HIV Treatment
COVID-19 and HIV remain significant global health challenges, with millions of people affected worldwide. Despite the availability of treatments, both viruses continue to spread, and neither has a definitive cure. A key issue lies in the viruses’ ability to exploit host cellular mechanisms, such as lipid rafts—specialized regions in cell...
Published: 5/12/2026   |   Updated: 12/10/2024   |   Inventor(s): Michael Bukrinsky, Dmitri Sviridov, Yury Miller
Keywords(s):  
Category(s): Technology Classifications > Therapeutics > Proteins and Peptides
Engineered Immune Cells for Targeted Tumor Infiltration and Enhanced CAR-T cell Therapy
CAR-T cell therapy has emerged as a promising cancer treatment, leveraging patient’s own T cells that are genetically modifying to express a Chimeric Antigen Receptor (CAR). These receptors enable T cells to recognize and attack antigens on the surface of cancerous cells more effectively. While highly effective against certain cancers, solid...
Published: 5/12/2026   |   Updated: 12/9/2024   |   Inventor(s): Rohan Fernandes, Bilal Omer, Stacey Van Pelt
Keywords(s):  
Category(s): Technology Classifications > Therapeutics > Cells, Technology Classifications > Therapeutics > Proteins and Peptides
Immunotherapies Targeting SSX2 Peptide Displayed by MHC on Tumors
­Chimeric Antigen Receptor (CAR) T cells are making headlines with their recent FDA approvals and ability to eradicate cancers. Most CAR T therapies target tumor cells via a tumor associated antigen (TAA). Unfortunately, TAAs are also expressed on non-cancerous tissues, leading to significant risk for patients. SSX2 protein expression is restricted...
Published: 5/12/2026   |   Updated: 1/13/2022   |   Inventor(s): Eric Yvon, Catherine Bollard, Stacey Van Pelt, Scott Raskin, Gerhard Held, Christine Sturm, Michael Pfreundschuh
Keywords(s):  
Category(s): Technology Classifications > Therapeutics > Proteins and Peptides
Optimization of Cold Atmospheric Plasma-Stimulated Media for Treatment of Cancer
Previously, GW researchers invented a method to selectively kill cancer cells with cold atmospheric plasma (CAP) while leaving neighboring normal cells intact. In a subsequent study, the researchers showed that similar anti-cancer effects can be achieved indirectly using CAP-stimulated media (CAPSM). Stability of CAPSM (preservation of its anti-cancer...
Published: 5/12/2026   |   Updated: 1/13/2022   |   Inventor(s): Dayun Yan, Michael Keidar, Jonathan Sherman
Keywords(s):  
Category(s): Technology Classifications > Therapeutics > Cells, Technology Classifications > Therapeutics > Proteins and Peptides, Technology Classifications > Therapeutics
Intranasal Oxytocin Therapy for Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is a health risk that occurs in 24% of males and 9% of females in the United States. OSA can lead to several cardiovascular diseases including hypertension, arrhythmia, and stroke. Continuous positive airway pressure (CPAP) treatments often fail due to low compliance. GW Researchers developed an intranasal oxytocin administration...
Published: 5/12/2026   |   Updated: 1/13/2022   |   Inventor(s): David Mendelowitz, Heather Jameson, Vivek Jain, Jay Kimbro
Keywords(s):  
Category(s): Technology Classifications > Medical Devices > Cardiology, Technology Classifications > Therapeutics > Proteins and Peptides