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ERG-7 Inhibitors: Targeting the Sterol Biosynthetic Pathway

This invention relates to small molecule anti-fungal compounds, pharmaceutical compositions, and methods of use for the prevention, treatment, or mitigation of fungal diseases in human and veterinary subjects. In particular aspects, the invention provides inhibitors that modulate fungal sterol biosynthesis, including inhibitors of lanosterol synthase...

Published: 5/6/2026 | Updated: 5/6/2026 | Inventor(s): Rui Xiong, Hongmin Li, Malla Reddy Gannarapu, Divakar Indukuri, Anil Tharappel, Ke Chen, Mengjiao Ma

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics

Fast, Background-free Detection of Nucleic Acid Sequences Using DNA Nanoswitches

This technology introduces DNA-based "nanoswitches"—innovative nanostructures that enable precise and efficient detection of target analytes through conformational changes. Background: Accurate detection of specific molecules, such as DNA sequences or other analytes, is fundamental in medical diagnostics, environmental monitoring,...

Published: 5/6/2026 | Updated: 5/5/2026 | Inventor(s): Kenneth Halvorsen, Wesley Wong, Arun Richard Chandrasekaran

Keywords(s):

Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering

nsP2 Inhibitors: Targeting the Alphavirus nsP2 Protease

This invention relates to antiviral compounds targeting the alphavirus nsP2 protease, pharmaceutical compositions, and methods of use for the prevention, treatment, or mitigation of the Chikungunya virus. This compound selectively interferes with the essential proteolytic processing activity of nsP2, a critical step in the viral life cycle. By blocking...

Published: 4/29/2026 | Updated: 4/29/2026 | Inventor(s): Hongmin Li, Rui Xiong, Subodh Samrat, Malla Reddy Gannarapu, Ran Zhang, Ke Chen, Mengjiao Ma, Omar Alejandro Lozano Ramos, Divakar Indukuri, Renu Bhardwaj

Keywords(s):

Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Small Molecules

DNA Methylation-Based Cancer Diagnostics for Accurate Tumor Classification

Summary: The National Cancer Institute (NCI) seeks research co-development partners and/or licensees for a collection of T-cell receptors (TCRs) that specifically target the mutated KRAS antigen. This technology encompasses a DNA methylation–based diagnostic platform designed to improve the accuracy and consistency of cancer classification,...

Published: 4/23/2026 | Updated: 4/10/2026 | Inventor(s): Kenneth Aldape, Ziedulla Abdullaev, Rustamzhon Turakulov, Stefania Pittaluga, Mark Raffeld, Elaine Jaffe, Omkar Singh, Antonios Papanicolau-Sengos

Keywords(s):

Category(s): Application > Diagnostics, TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Nano-Fern Structured Silver-Copper Electrodes for Electrochemical Reductive Technologies

Invention Description Over the last century, human activity has profoundly disrupted the natural nitrogen cycle, driven largely by the widespread use of ammonia (NH3) produced via the Haber–Bosch (HB) process. While this method is crucial for sustaining the global population, it is highly energy-intensive, requiring extreme temperatures and pressures,...

Published: 3/31/2026 | Updated: 3/31/2026 | Inventor(s): Sergio Garcia-Segura, Kenneth Flores

Keywords(s):

Category(s): Advanced Materials/Nanotechnology, Environmental Remediation/Wastewater Treatment, Environmental, Physical Science

Improving the sensitivity and range of detection with ligation of DNA nanoswitches

This technology uses enzymatic ligation in DNA nanoswitches to detect very short or rare DNA and RNA sequences with high sensitivity, amplifying signals by recycling targets so even single molecules can be identified for diagnostics and research. Background: Nucleic acid detection is a cornerstone of modern molecular biology, diagnostics, and biotechnology,...

Published: 3/26/2026 | Updated: 3/11/2026 | Inventor(s): Kenneth Halvorsen, Jibin Punnoose, Vinod Morya

Keywords(s): DNA nanoswitches, Technologies

Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Biomedical Science and Engineering

A 3D printable mini-gel electrophoresis system and methods for use

This technology is a low-cost, 3D printable mini-gel electrophoresis system with built-in electrodes, enabling rapid, portable DNA analysis using battery power—ideal for education, fieldwork, and labs with limited resources. Background: Gel electrophoresis is a cornerstone technique in molecular biology, widely used for the separation and analysis...

Published: 3/26/2026 | Updated: 3/9/2026 | Inventor(s): Kenneth Halvorsen, Andrew Hayden, Vinod Morya

Keywords(s): 3D printing, Technologies

Category(s): Campus > University at Albany, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics

Expanding DNA nanoswitch utility with detection by aptamers

This technology integrates aptamers into DNA nanoswitches, enabling sensitive detection of a wide range of biomolecules—including proteins and small molecules—for use in diagnostics, research, and biosensing applications. Background: Molecular detection technologies are foundational in fields such as diagnostics, biomedical research,...

Published: 3/26/2026 | Updated: 3/9/2026 | Inventor(s): Kenneth Halvorsen, Arun Richard Chandrasekaran

Keywords(s): aptamers, DNA nanoswitches, Technologies

Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Biomedical Science and Engineering

Methods for detecting RNA modifications with DNA nanoswitches

This technology uses DNA nanoswitches to directly and specifically detect RNA modifications, allowing simultaneous identification of multiple modifications in their natural sequence context for research, diagnostics, and drug discovery applications. Background: RNA modifications, such as methylation, play critical roles in gene regulation, cellular...

Published: 3/26/2026 | Updated: 3/9/2026 | Inventor(s): Kenneth Halvorsen, Iranna Todkari, Andrew Hayden

Keywords(s): DNA nanoswitches, RNA modifications, Technologies

Category(s): Campus > University at Albany, Technology Classifications > Diagnostics, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Drug Design and Synthesis

Mechanically Tunable Engineered Heart Tissue Platform

Next-generation engineered heart tissue platform that enables precise tuning of mechanical properties of microenvironment to study the structure, development, and function of cultured cells or human-derived cardiac tissues. Problem: Engineering heart tissue (EHT) platforms have the potential to study heart physiology, disease pathology, and therapeutic...

Published: 1/30/2026 | Updated: 1/30/2026 | Inventor(s): Kenneth Margulies, Benjamin Lee, Nesrine Bouhrira

Keywords(s): Bioengineering, Cardiovascular, Drug Target, Platform Technology

Category(s): Technology Classifications > Hardware & Components, Technology Classifications > Research Tools & Reagents, Technology Classifications > Testing & Measurement

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